Temp - Associate Scientist - Biology

Neomorph•San Diego, CA

About The Position

Neomorph is seeking an experienced associate scientist with a passion for drug discovery and extensive experience with routine molecular and cell biology techniques. The role will be critically involved in supporting our Neomorph's internal pipeline through contributions to both target identifcation and validation efforts, as well as by enabling decision-making through generation of robust data packages. The successful applicant will be an integral member of project teams and will be responsible for communicating broadly across the organization.

Requirements

MS with 5+ years, or BS with 8+ years of industry experience
Track record of supporting preclinical drug discovery with robust data packages: includes evaluation of novel targets/pathways for therapeutic potential and/or characterization of compounds in relevant disease models
Proficiency with routine cell and molecular biology techniques including tissue culture, qRT-PCR, western blotting, and ELISA
Experience with cell-based assay development, optimization, and troubleshooting including plate-based high throughput readouts (e.g. luminescence, fluorescence)
Experience with cell line engineering strategies (RNAi, CRISPR, lentiviral transduction)
Excellent verbal and written communication and interpersonal skills
Desire and capacity to participate in a dynamic and fast-paced research setting
Desire and capacity to work collaboratively as part of a multidisciplinary team
Experience with targeted protein degradation
Demonstrated proficiency with contemporary plasmid cloning techniques
Experience with HTS-enabling technologies (e.g. liquid handlers, compound dispensers)

Nice To Haves

Experience with targeted protein degradation
Demonstrated proficiency with contemporary plasmid cloning techniques
Experience with HTS-enabling technologies (e.g. liquid handlers, compound dispensers)

Responsibilities

Profile the biological activities of lead compounds in relevant cellular models/assays
Delineate mechanisms of sensitivity and resistance to refine understanding of desired compound profiles using both chemical and genetic approaches
Assess glue degrader mechanism of action using established assays
Elucidate biological mechanisms of action that confer pharmacodynamic effects of lead compounds
Support molecular and cell biology platforms for target identification and validation through plasmid cloning and cell line engineering
Communicate results and solicit effectively in a variety of internal settings

Benefits

Industry competitive compensation
Career advancement opportunities
Monthly town halls to share business and scientific updates
Work Hard, Stay Well
Comprehensive medical, dental, and vision plans for employees and their dependents
Health and Dependent Care FSA and HSA Plan with monthly Neomorph contribution
Employee Assistance Program
10 holidays + Winter Shutdown + 3 weeks of vacation time with additional accruals after 2nd year of employment, separate sick leave.
Supplemental pay for Pregnancy Disability Leave
Paid Parental Leave for employees with a newborn child or a child placed with them for adoption or foster care
Lifestyle
Casual work environment
Flexible work schedule
Onsite space to store your bicycle (or surfboard)
Have Fun!
We believe in work/life balance and Fun is at the core of our Core Values. In addition to department and company happy hours, we have regular company-wide and department lunches and social events (ie Padres games, summer picnic, holiday party, bring your kids to work day).