Associate Scientist - Analytical & Bioanalytical Mass Spectrometry (ABMS)

Regeneron Pharmaceuticals • Tarrytown, GA

2d • Onsite

About The Position

Regeneron Pharmaceutical's Analytical and Biological Mass Spectrometry Group (ABMS), located in Tarrytown, NY is seeking a motivated Associate Scientist to join our fast-paced and interdisciplinary team working on analytical and bioanalytical development on novel siRNA/oligonucleotide-based modalities in a diverse genetic medicine pipeline. A Typical Day in the Role Might Look Like: Develop and optimize liquid chromatography coupled to mass spectrometry (LC-MS) related methods for the enrichment, detection, quantification, and structural characterization of siRNAs, oligonucleotides, novel siRNA conjugates and monoclonal antibodies (mAbs) Perform analytical testing and sample preparation of siRNA/oligonucleotides with a focus on chromatographic fractionation, LC, LC-MS, solid phase extraction (SPE), hybridization-capture, and other mass spectrometry related methods Independently conduct sample preparation and LC-MS analyses in compliance with SOPs or drafted protocols, and document experimental procedures and results in electronic laboratory notebook (ELN) This Role May Be For You If: You are mentally flexible and adapt quickly to changing priorities in a fast-paced environment. You are an excellent team player who can follow directions while also bringing your own insights to problem-solving. You have a growth mindset and eagerly embrace new challenges and learning opportunities. You are interested in learning about genetic medicines and development for impactful RNA-based therapies. This role requires a BS or MS degree in Chemistry, Biochemistry, Pharmaceutical Sciences, or a related field with 0–3 years of relevant hands‑on laboratory experience in analytical chemistry or bioanalytical sciences. Strong hands-on experience with liquid chromatography (such as reversed-phase, size-exclusion, ion exchange chromatography) is essential, particularly HPLC or UPLC techniques. Hands-on experience with various types of biological matrices is a plus. Hands-on experience with fractionation, solid phase extraction and/or hybridization techniques would be particularly valuable. While mass spectrometry experience is beneficial, we prioritize candidates with excellent chromatography skills and the ability to optimize separation methods. You should be comfortable working independently after initial guidance and be able to communicate effectively about technical challenges and results. Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive culture that provides comprehensive benefits, which vary by location. In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels! For additional information about Regeneron benefits in the US, please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other countries’ specific benefits, please speak to your recruiter. Please be advised that at Regeneron, we believe we are most successful and work best when we are together. For that reason, many of Regeneron’s roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about Regeneron’s on-site policy and expectations for your role and your location. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business. For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location. Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc. Salary Range (annually) $93,900.00 - $153,300.00 Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led for over 30 years by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to nine FDA-approved treatments and numerous product candidates in development, almost all of which were homegrown in our laboratories. Our medicines and pipeline are designed to help patients with eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, neurology, infectious diseases and rare diseases. Regeneron is also proud of award winning culture of innovation, being recognized as a Great Place to Work in 2021, Fast Company’s Best Workplace for Innovators in 2020, and Forbes JUST companies in 2020, among others.

Requirements

• BS or MS degree in Chemistry, Biochemistry, Pharmaceutical Sciences, or a related field with 0–3 years of relevant hands‑on laboratory experience in analytical chemistry or bioanalytical sciences.
• Strong hands-on experience with liquid chromatography (such as reversed-phase, size-exclusion, ion exchange chromatography) is essential, particularly HPLC or UPLC techniques.
• You should be comfortable working independently after initial guidance and be able to communicate effectively about technical challenges and results.

Nice To Haves

• Hands-on experience with various types of biological matrices is a plus.
• Hands-on experience with fractionation, solid phase extraction and/or hybridization techniques would be particularly valuable.
• While mass spectrometry experience is beneficial, we prioritize candidates with excellent chromatography skills and the ability to optimize separation methods.

Responsibilities

• Develop and optimize liquid chromatography coupled to mass spectrometry (LC-MS) related methods for the enrichment, detection, quantification, and structural characterization of siRNAs, oligonucleotides, novel siRNA conjugates and monoclonal antibodies (mAbs)
• Perform analytical testing and sample preparation of siRNA/oligonucleotides with a focus on chromatographic fractionation, LC, LC-MS, solid phase extraction (SPE), hybridization-capture, and other mass spectrometry related methods
• Independently conduct sample preparation and LC-MS analyses in compliance with SOPs or drafted protocols, and document experimental procedures and results in electronic laboratory notebook (ELN)

Benefits

• health and wellness programs (including medical, dental, vision, life, and disability insurance)
• fitness centers
• 401(k) company match
• family support benefits
• equity awards
• annual bonuses
• paid time off
• paid leaves (e.g., military and parental leave)

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Number of Employees: 5,001-10,000 employees