Associate Researcher I-Pathology Molecular and Cell Based Medicine

Mount Sinai Health System • New York, NY

18h

About The Position

We are seeking a highly motivated individual to work as a research assistant in a translational neuropathology research laboratory. The laboratory is directed by Dr. John F. Crary, MD-PhD, and focuses on the underlying neuropathology and genetics of Alzheimer's Disease and related neurodegenerative disorders (e.g., chronic traumatic encephalopathy, Parkinson’s disease, etc.). The laboratory uses a variety of techniques, including DNA/RNA sequencing, stem cell culture, histology and digital neuropathology, confocal microscopy, optogenetics, and biochemistry. Individuals will be trained to deploy these approaches to diagnose and study brain diseases and gain exposure to challenges associated with treatment modalities, diagnosis, and research design. This role assists with the technical aspects of studies and experiments with potential opportunities to attend and present at conferences and contribute to publications. The individual will have opportunities to interface with both clinical staff and basic scientists, making the position ideal for someone who is interested in broad exposure to the challenges associated with diagnosing, treating, and studying degenerative brain diseases. Responsibilities Assists with experiments including data collection and entry, maintaining data records, and analysis Performing cell culture techniques including primary fibroblast banking and maintenance of stem cell lines and organoid models in preparation for downstream experiments and screening assays Immunohistochemistry, immunocytochemistry, and microscopy for brain tissue and stem cell projects Performing general molecular biology and protein biochemistry techniques e.g., PCR, RT-PCR, isolation of genomic DNA and RNA from cells and brain tissue, western blotting Directly supports the initiatives of the Neuropathology Brain Bank and Research CoRE Reports directly to the supervising neuropathologist and works closely with staff scientists, postdoctoral fellows, project coordinators, trainees and technical staff to ensure the success of projects Ensure lab conditions and equipment complies with established safety procedures and maintains required documentation on lab safety

Requirements

• Bachelor’s degree in a science-related discipline required, such as Neuroscience, Biology, Chemistry, Psychology, etc.
• Applicants must have experience working in a lab environment
• Applicants should have an interest or background in neuroscience and brain research
• Excellent organizational, interpersonal and communication skill
• Minimum two-year commitment

Responsibilities

• Assists with experiments including data collection and entry, maintaining data records, and analysis
• Performing cell culture techniques including primary fibroblast banking and maintenance of stem cell lines and organoid models in preparation for downstream experiments and screening assays
• Immunohistochemistry, immunocytochemistry, and microscopy for brain tissue and stem cell projects
• Performing general molecular biology and protein biochemistry techniques e.g., PCR, RT-PCR, isolation of genomic DNA and RNA from cells and brain tissue, western blotting
• Directly supports the initiatives of the Neuropathology Brain Bank and Research CoRE
• Reports directly to the supervising neuropathologist and works closely with staff scientists, postdoctoral fellows, project coordinators, trainees and technical staff to ensure the success of projects
• Ensure lab conditions and equipment complies with established safety procedures and maintains required documentation on lab safety

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Number of Employees: 5,001-10,000 employees