Associate Director, Statistical Programming

Kymera Therapeutics • Watertown, MA

1d • $160,000 - $240,000

About The Position

Kymera Therapeutics is seeking an experienced and strategic Associate Director of Statistical Programming to lead programming efforts across multiple clinical studies. This role will be instrumental in ensuring high-quality, timely, and compliant statistical deliverables in support of Kymera’s innovative degrader pipeline. The ideal candidate has a deep understanding of clinical trial conduct, data flow, and regulatory expectations, and is comfortable being 50% hands-on in programming. This individual will proactively identify risks, solve complex problems, and collaborate effectively with cross-functional stakeholders and external partners.

Requirements

• MS or equivalent degree in Statistics, Biostatistics, Computer Science, or related field.
• 8+ years of statistical programming experience in the pharmaceutical or biotechnology industry, including experience supporting late-phase (Phase II and III) clinical trials.
• Proven experience overseeing CROs and external vendors, with accountability for quality, timelines, and deliverables.
• Deep, hands-on expertise with CDISC standards (SDTM, ADaM) and strong knowledge of regulatory submission requirements (e.g., NDA/MAA).
• Proven ability to independently produce high-quality analysis datasets, tables, listings, and figures for data request.
• Strong expertise in programming and analyzing efficacy endpoints, with the ability to efficiently translate clinical objectives into analysis-ready datasets and outputs.
• Demonstrated ability to collaborate effectively in cross-functional settings and manage competing priorities in a fast-paced or startup environment
• Proactive, solutions-oriented mindset with excellent communication and leadership skills.

Nice To Haves

• R or Python is plus

Responsibilities

• Lead across multiple studies or a clinical program, ensuring timely, accurate, and regulatory-compliant deliverables, including oversight of SDTM, ADaM, and TLF deliverables by vendors.
• Collaborate closely with internal study team and external partners to ensure alignment on timelines, priorities, and quality expectations.
• Oversee CRO deliverables as needed, with a focus on technical quality and consistency, ensuring clear documentation of the process
• Develop, validate, and maintain datasets (SDTM, ADaM), tables, listings, and figures, TLFs) in accordance with regulatory guidelines and internal standards to assist with data review, CSR, annual data report, publication, in-house data request, etc
• Provide expertise in statistical programming for regulatory submissions (e.g., FDA, EMA), including electronic submission standards (eCTD)
• Coordinate and schedule data transfers and delivery of required outputs as the lead or support programmer on studies
• Review key clinical study or program documents
• Manage multiple tasks, troubleshoot technical and project issues, and assist with the infrastructure development of the department; Evaluate and implement innovative tools and programming technologies to streamline processes and improve team efficiency and quality
• Stay current with industry trends, best practices, and emerging technologies in statistical programming and data analysis
• Additional duties and responsibilities as required

Benefits

• Kymera offers a competitive compensation package that recognizes both results and capabilities through market-based, performance-driven pay.
• The anticipated base salary range for this role is $160,000 – $240,000, with eligibility for annual bonus, equity participation, and comprehensive benefits.
• Actual salary is based on a holistic evaluation of the specific role/level as well as each candidate’s depth of experience and the capabilities they bring to the position.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 101-250 employees