Associate Director, Precision Medicine

Regeneron Pharmaceuticals • Village of Tarrytown, NY

6d

About The Position

The Associate Director in Precision Medicine works closely with key clinical and research personnel to take ownership of and execute the Precision Medicine strategy and clinical biomarkers for programs with a focus on the support of Regeneron's Immunology & Inflammation (I&I) and Ophthalmology pipelines. The successful candidate will lead clinical biomarker and translational efforts, including academic and commercial collaborative programs. Technologies will be applied strategically with the goal of expediting proof-of-concept for new drug candidates and combinations, assessment of PK/PD relationships, optimization of label claims, and enabling precision medicine principles to be applied, as appropriate, in full development. The Associate Director will collaborate with the clinical diagnostic leads, development team leads, preclinical research teams, technology center colleagues, clinical & precision medicine operations, partners from allied companies, and senior management. A typical day may include: Lead Precision Medicine (clinical biomarker) strategy development and execution to support the clinical development portfolio, including biomarker driven clinical study design, implementation of novel technologies and incorporation of biomarker endpoints. Lead biomarker development and implementation through the application of genomic (RNA and DNA sequencing), protein and cell/tissue analysis, and clinical device technologies, as needed Champion early-adoption of biomarker strategy for pipeline pre-clinical programs and generate proposals for clinical experimental sciences studies, in close collaboration with Clinical Sciences, I&I Research, and Regeneron Genetics Center (RGC) colleagues. Represent Precision Medicine on cross-functional strategic project teams and global clinical sub-teams across the development portfolio. Provide cross-functional team leadership of internal clinical biomarker discovery platform development (laboratory assays, computational biology methods), in collaboration with research, molecular profiling and genomics center teams. Present the clinical translational project plans, clinical trial protocols, biomarkers data and interpretation of results to internal stakeholders (including senior management), regulatory agencies and global opinion leaders, as needed. Evaluate emerging technologies and vendors to consider for future programs and to interpret data across programs. Willingness to work across multiple therapeutic areas, which may include but not be limited to Immunology & Inflammation, Ophthalmology and Infectious Disease This role may be for you if: The ability to drive, manage, complete and deliver results for complex multi-functional projects Excellent communication and presentation skills and high emotional intelligence, organizational skills and effective team skills

Requirements

• PhD and 6+ years of experience participating effectively on cross-disciplinary teams in pharmaceutical or biotech industry.
• The ability to drive, manage, complete and deliver results for complex multi-functional projects
• Excellent communication and presentation skills and high emotional intelligence, organizational skills and effective team skills

Nice To Haves

• Experience in clinical assay development, validation and implementation with strong experience in Immunology is preferred.

Responsibilities

• Lead Precision Medicine (clinical biomarker) strategy development and execution to support the clinical development portfolio, including biomarker driven clinical study design, implementation of novel technologies and incorporation of biomarker endpoints.
• Lead biomarker development and implementation through the application of genomic (RNA and DNA sequencing), protein and cell/tissue analysis, and clinical device technologies, as needed
• Champion early-adoption of biomarker strategy for pipeline pre-clinical programs and generate proposals for clinical experimental sciences studies, in close collaboration with Clinical Sciences, I&I Research, and Regeneron Genetics Center (RGC) colleagues.
• Represent Precision Medicine on cross-functional strategic project teams and global clinical sub-teams across the development portfolio.
• Provide cross-functional team leadership of internal clinical biomarker discovery platform development (laboratory assays, computational biology methods), in collaboration with research, molecular profiling and genomics center teams.
• Present the clinical translational project plans, clinical trial protocols, biomarkers data and interpretation of results to internal stakeholders (including senior management), regulatory agencies and global opinion leaders, as needed.
• Evaluate emerging technologies and vendors to consider for future programs and to interpret data across programs.
• Willingness to work across multiple therapeutic areas, which may include but not be limited to Immunology & Inflammation, Ophthalmology and Infectious Disease

Benefits

• comprehensive benefits, which vary by location. In the U.S., benefits may include health and wellness programs (including medical, dental, vision, life, and disability insurance), fitness centers, 401(k) company match, family support benefits, equity awards, annual bonuses, paid time off, and paid leaves (e.g., military and parental leave) for eligible employees at all levels!

What This Job Offers

• Job Type: Full-time
• Career Level: Director
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees