Associate Director, Biologics

Johnson & Johnson•Spring House, PA

4d•Onsite

About The Position

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com Job Function: Discovery & Pre-Clinical/Clinical Development Job Sub Function: Biotherapeutics R&D Job Category: People Leader All Job Posting Locations: Spring House, Pennsylvania, United States of America Job Description: About Innovative Medicine Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine We are searching for the best talent for an Associate Director, Biologics in Spring House, PA. Purpose: Are you a passionate scientific leader with expertise in protein expression, molecular biology and biochemistry? Are you an empathetic leader who recognizes the contributions of others and brings out the best in people? If so, then Johnson & Johnson Innovative Medicine is recruiting an Associate Director for the Expression Sciences team within Therapeutics Discovery. Our department is a central piece to our discovery engine, generating our therapeutic candidates, including ground-breaking multispecific antibodies and antibody drug conjugates. We strive to capitalize on our talents to discover next-generation medicines to help patients in need. The Associate Director will lead a team of scientists to express complicated proteins, engineer mammalian cells, innovate upstream processes, and deliver creative research solutions to formidable drug discovery challenges. You will be responsible for:

Requirements

A minimum Ph.D. in molecular biology, biochemistry, cell biology or similar field with a minimum of 6 years of pharmaceutical industry experience is required.
Evidence of people management of multiple personnel is required.
Included in this is experience with coaching development plans, payroll, and hiring.
Recombinant protein expression expertise is required, including hands-on experience with methods like mammalian cell culture (CHO & HEK293), transfection, and bioreactors.
Excellent interpersonal skills, both written and verbal, with the ability to convey nuanced information clearly to senior management is required.
Proficiency with electronic notebooks (ELN), databases and laboratory information management systems (LIMS) is strongly preferred.

Nice To Haves

Expertise in molecular biology including cloning approaches, RNA seq, ATAC-seq, ChIP-seq, or CRISPR mutagenesis is highly sought after.
Practical experience purifying recombinant proteins using Akta systems with affinity chromatography, IEX, HIC, and MMC is preferred.
Experience with analytical methods such as HPLC, CE-SDS, SDS PAGE, BLI, and proteomic approaches is strongly preferred.
Expertise with big data modeling and bioinformatics is especially desired.
Experience working on multiplexed teams is preferred.

Responsibilities

Lead and mentor a team responsible for expressing candidate biotherapeutic molecules in stable mammalian cell culture systems.
As a protein expression expert, interpret complex datasets to identify and mitigate risks as part of our discovery process.
Creatively identify drug developability trends by modeling large datasets.
Identify value-adding innovative protein production capabilities, industry trends, and emerging technologies and work to evaluate these.
Lead creative research efforts (e.g. using ‘omics and screens) to maximize efficiency and maintain our organizational competitiveness.
Collaborate across our company’s global functions to discover innovative medicines.
Communicate regularly and accurately within the department and with company leadership to drive rapid, impactful decision making.
Lead drug discovery projects and research initiatives, ensuring alignment with the company’s strategic goals.
Prepare and present reports, proposals, and primary data to senior management and partners.
Coordinate and present timelines and deliverables with a wide range of partners and stakeholders.
As a leader at J&J, foster a culture of continuous improvement, innovation, learning and development.