Assistant Research Professor

City of Hope•Duarte, CA

38d

About The Position

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research. As Assistant Research Professor is available in the Beckman Research Institute of City of Hope. This is a part time position working for 8 hours a week. City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location. City of Hope is an equal opportunity employer.

Requirements

PhD, MD, or MD/PhD with a strong background in molecular biology, genome editing, or gene therapy.
Extensive experience in molecular biology and genomics, designing and optimizing gene editing and gene augmentation vectors for in vivo and in vitro applications.
Evidence of scientific rigor and excellence as documented by high-impact peer-reviewed publications.
Prior experience in translational research and preclinical model development.
Demonstrated ability to mentor research associates and technical staff in a laboratory environment.
Proven track record of collaborative research and contribution to innovative therapeutic strategies.

Responsibilities

Design optimized genome editing and gene augmentation vectors for the treatment of genetic diseases, including hypertrophic cardiomyopathy (HCM).
Design vectors to correct specific pathogenic mutations in target genes in in vivo disease models.
Create vectors for the targeted insertion of reporters and correction of mutations at specified genomic locations in target genes across species.
Develop strategies to codon-optimize correction sequences to achieve desired expression levels and optimize editing efficiency.
Develop strategies to evaluate the outcome of genetic therapies.
Oversee and guide the cloning of genetic vectors.

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