Analytical Development Intern (Graduate-Level)
About The Position
We are looking for Master's and Doctoral students studying Biochemistry, Chemistry or Analytical Chemistry, Chemical Engineering, Molecular Biology, Pharmaceutical Science, Bioengineering/Biotechnology, or a related discipline for a 12-week internship role at our Alexion: AstraZeneca Rare Disease site in New Haven, CT from June 1 2026 to August 21 2026. Position Description: Lead and execute comparability and forced degradation studies, including study design, sample preparation, data analysis, and reporting. Lead and perform enrichment, fractionation, and characterization of protein variants (e.g., charge and size variants) using techniques such as SEC, CE-SDS, IEX, and MS. Develop, optimize, and document analytical/characterization methods for biotherapeutic candidates, including drafting protocols/reports and establishing system suitability/acceptance criteria.
Requirements
- Master's and Doctoral students studying Biochemistry, Chemistry or Analytical Chemistry, Chemical Engineering, Molecular Biology, Pharmaceutical Science, Bioengineering/Biotechnology , or a related discipline
- Candidates must have an expected graduation date after August 2026.
- Basic laboratory skills such as pipetting and dilution required
- US Work Authorization is required at time of application.
- Ability to report onsite to New Haven, CT site 4-5 days per week. This role will not provide relocation assistance.
Nice To Haves
- Knowledge and understanding of separation science, including liquid chromatography (Size-Exclusion Chromatography, Ion-Exchange Chromatography)/Capillary Isoelectric Focusing/Imaged Capillary Electrophoresis is preferred
- Enthusiasm for collaboration, cross-functional projects, public speaking, and presentation design.
Responsibilities
- Lead and execute comparability and forced degradation studies, including study design, sample preparation, data analysis, and reporting.
- Lead and perform enrichment, fractionation, and characterization of protein variants (e.g., charge and size variants) using techniques such as SEC, CE-SDS, IEX, and MS.
- Develop, optimize, and document analytical/characterization methods for biotherapeutic candidates, including drafting protocols/reports and establishing system suitability/acceptance criteria.
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What This Job Offers
Career Level
Intern
Number of Employees
5,001-10,000 employees
