Advisor, Immunoassay-based Biomarker Discovery and Analysis - Neuroscience

Eli Lilly and CompanyBoston, MA
5d$138,000 - $224,400Onsite

About The Position

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. Analyses as part of the development and validation of novel immunoassay-based biomarker methods, as well as apllications of these methods for clinical trials in neurodegenerative diseases, including Alzheimer’s, Parkinson’s, ALS, and rare brain disorders. Work with project team leads, including Dr. Kaj Blennow (Vice President of Neuroscience Biomarker Development), and other associates to perform experiments to support both the preclinical and clinical characterization and evaluation of therapeutic molecules through biomarker assay development. Assist with the planning and execution of immunoassay method developments, method optimization and validation, as well as sample analyses from different preclinical samples sets and clinical cohorts. Work directly on-site with methods in the laboratory, and with summarizing and reporting method status of results for internal partners. Implement assay validation procedures to deliver high performance biomarker assays for preclinical and clinical sample analyses.

Requirements

  • Bachelor’s degree in relevant area, with experience in protein biomarker analysis and with 5+ years of industry, academic
  • Additional or postdoctoral experience experience in biomarker development, with recognized expertise in immunoassay-based methods

Nice To Haves

  • Must be technically skilled to in the field of qualitative (e.g. electrophoresis techniques, Westen blot) and quantitative (e.g. ELISA, MSD, Ella, Simoa, NULISA, SpearBio) immunoassay-based analyses
  • Must have an understanding of the principles for immunoassays (e.g. antibodies and other ligand-based molecules, assay design), protein biomarker quantification, assay validation, as well as documented hands-on experience in protein biomarker applications (e.g. clinical diagnostics, clinical trials, or preclinical sample analysis)

Responsibilities

  • Analyses as part of the development and validation of novel immunoassay-based biomarker methods
  • Applications of these methods for clinical trials in neurodegenerative diseases, including Alzheimer’s, Parkinson’s, ALS, and rare brain disorders
  • Work with project team leads, including Dr. Kaj Blennow (Vice President of Neuroscience Biomarker Development), and other associates to perform experiments to support both the preclinical and clinical characterization and evaluation of therapeutic molecules through biomarker assay development
  • Assist with the planning and execution of immunoassay method developments, method optimization and validation, as well as sample analyses from different preclinical samples sets and clinical cohorts
  • Work directly on-site with methods in the laboratory, and with summarizing and reporting method status of results for internal partners
  • Implement assay validation procedures to deliver high performance biomarker assays for preclinical and clinical sample analyses

Benefits

  • Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance)
  • Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)

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What This Job Offers

Job Type

Full-time

Career Level

Mid Level

Number of Employees

5,001-10,000 employees

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