2026 Summer Intern - Translational Pharmacokinetics & Pharmacodynamics

Genentech•Daly City, CA

16d•$46•Onsite

About The Position

2026 Summer Intern - Translational Pharmacokinetics & Pharmacodynamics Department Summary This intern position is in the Translational Pharmacokinetics & Pharmacodynamics (tPKPD) Department within Development Sciences. The tPKPD department applies preclinical models (in silico, in vitro or in vivo) to determine the pharmacokinetics (what the body does to the drug) and/or pharmacodynamics (what the drug does to the body) of biotherapeutics. The information obtained from such work is often used to help select lead molecules, optimize dosing regimens and understand the PK behavior/metabolic fate of different molecular designs as we help advance molecules through stages of research and into early clinical development. The work within the tPKPD department spans across a wide range of disease areas, including oncology, immunology, ophthalmology, infectious disease and neuroscience. This internship position is located in South San Francisco, on-site. The Opportunity We are seeking a highly motivated intern to join the tPKPD Department at Genentech. The intern will: Develop organ-on-chip, physiology-based models to investigate key pharmacokinetic mechanisms. Apply cell biology and high-content confocal imaging techniques to study intracellular processing of large-molecule therapeutics. Contribute to the development of innovative experimental approaches for predictive PK investigation. Gain hands-on exposure to cell biology, high-content imaging, and biotherapeutic drug development. Summarize findings in written reports and present results at departmental meetings and the company-wide intern poster session. Program Highlights Intensive 12-weeks, full-time (40 hours per week) paid internship. Program start dates are in May/June 2026. A stipend, based on location, will be provided to help alleviate costs associated with the internship. Ownership of challenging and impactful business-critical projects. Work with some of the most talented people in the biotechnology industry. Who You Are Required Education: Must be pursuing a PhD (enrolled student). Required Majors: Cell Biology; Bioengineering / Biomedical Engineering; Pharmacology; Pharmaceutical Sciences or related fields. Required Skills: Proficiency in cell culture, cell staining, and standard laboratory techniques, with the ability to multitask and meet timelines efficiently and productively. Prior experience with complex primary cell culture, in vitro cell-based systems, or organ-on-chip models is highly desired. Experience with confocal microscopy or high content imaging is highly desired. Solid experience in experimental design and execution, data analysis, interpretation, and documentation, with keen attention to detail. Preferred Knowledge, Skills, and Qualifications Excellent communication, collaboration, and interpersonal skills. Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion. Relocation benefits are not available for this job posting. The expected salary range for this position based on the primary location of California is $46.00 hour. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits. Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws. If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

Requirements

Must be pursuing a PhD (enrolled student).
Cell Biology; Bioengineering / Biomedical Engineering; Pharmacology; Pharmaceutical Sciences or related fields.
Proficiency in cell culture, cell staining, and standard laboratory techniques, with the ability to multitask and meet timelines efficiently and productively.
Solid experience in experimental design and execution, data analysis, interpretation, and documentation, with keen attention to detail.

Nice To Haves

Prior experience with complex primary cell culture, in vitro cell-based systems, or organ-on-chip models is highly desired.
Experience with confocal microscopy or high content imaging is highly desired.
Excellent communication, collaboration, and interpersonal skills.
Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.

Responsibilities

Develop organ-on-chip, physiology-based models to investigate key pharmacokinetic mechanisms.
Apply cell biology and high-content confocal imaging techniques to study intracellular processing of large-molecule therapeutics.
Contribute to the development of innovative experimental approaches for predictive PK investigation.
Gain hands-on exposure to cell biology, high-content imaging, and biotherapeutic drug development.
Summarize findings in written reports and present results at departmental meetings and the company-wide intern poster session.