2026 Summer Intern - Regev Lab - Complex Communication
About The Position
Colorectal cancer progression is driven not only by tumor-intrinsic genetic mutations, but also by how those mutations remodel the surrounding tumor microenvironment (TME) and cell-to-cell communications. This project aims to decipher the complex communication between cancer cells, immune cells, and fibroblasts using a physiological in vivo model. By employing inducible gene-editing technologies combined with optical pooled screens (OPS) and multimodal spatial phenotyping, we seek to understand how specific genetic perturbations allow tumors to manipulate their surroundings. This internship position is located in South San Francisco, on-site. The Opportunity The intern will play a key role in the execution and analysis phase of this study, with a primary focus on processing and integrating high-dimensional sequencing and spatial imaging datasets. Depending on the candidate's background and interest, the role may also include experimental work such as tumor harvesting, tissue sectioning, and library preparation. The expected outcome is a high-resolution spatial map of tumor-immune interactions. The project is estimated to take 3 months, with the possibility of an extension to 6 months for follow-up studies. Program Highlights Intensive 12-weeks, full-time (40 hours per week) paid internship. Program start dates are in May/June 2026. A stipend, based on location, will be provided to help alleviate costs associated with the internship. Ownership of challenging and impactful business-critical projects. Work with some of the most talented people in the biotechnology industry.
Requirements
- Must be pursuing a PhD (enrolled student).
- Bioinformatics, Computational Biology, Molecular Biology, Immunology, or a related field.
- Sequencing Data Analysis (for computational candidates): Proficiency in analyzing high-dimensional sequencing datasets and identifying key biological perturbations.
- Multimodal Data Integration (for computational candidates): Ability to assist in aligning sequencing data with spatial imaging results to interpret complex cell-cell interactions.
- Genomics & Tissue Techniques (for experimental candidates): Experience with tissue processing, library preparation, and molecular biology techniques is required.
- Tumor Biology & Immunology: A strong foundational knowledge of cancer biology or immunology to help interpret the biological significance of screen results.
- Communication & Collaboration: Strong skills in documenting analytical pipelines and collaborating effectively within a multidisciplinary team of biologists and data scientists.
Nice To Haves
- Excellent communication, collaboration, and interpersonal skills.
- Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.
Responsibilities
- Processing and integrating high-dimensional sequencing and spatial imaging datasets.
- Experimental work such as tumor harvesting, tissue sectioning, and library preparation (depending on background and interest).
Benefits
- paid holiday time off benefits
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What This Job Offers
Job Type
Full-time
Career Level
Intern
Education Level
Ph.D. or professional degree
