2026 Summer Intern – Biochemical & Cellular Pharmacology, Biophysics

RocheSouth San Francisco, CA
2d$29 - $46Onsite

About The Position

The department of Biochemical and Cellular Pharmacology (BCP) develops relevant quantitative biochemical and cellular assays and experiments to support both biological and small molecule drug discovery efforts at Genentech. Working as integrated members of multi-disciplinary project teams, we will apply scholarly, rigorous methodology to define and characterize optimal leads and to define in vitro biological strategies that will enhance Genentech's Discovery pipeline of therapeutic antibodies and small molecule clinical candidates. We are seeking a talented individual to join the Biophysics group in BCP as a Summer Intern to help develop biophysical methodologies for challenging protein targets. This internship position is located in South San Francisco, on-site. The Opportunity The successful candidate will develop methods utilizing Surface Plasmon Resonance (SPR) to characterize interactions between challenging protein targets and small molecules. Explore protein engineering and other biophysical techniques that can impact early chemical matter progression. Obtain exposure to critical assays and strategies in early drug discovery. Program Highlights Intensive 12-weeks, full-time (40 hours per week) paid internship. Program start dates are in May/June 2026. A stipend, based on location, will be provided to help alleviate costs associated with the internship. Ownership of challenging and impactful business-critical projects. Work with some of the most talented people in the biotechnology industry.

Requirements

  • Must be pursuing a Bachelor's Degree (enrolled student).
  • Must have attained a Bachelor's Degree (not currently enrolled in a graduate program).
  • Must be pursuing a Master's Degree (enrolled student).
  • Must have attained a Master's Degree.
  • Must be pursuing a PhD (enrolled student).
  • Biochemistry, Biophysics, Chemical Engineering, Bioengineering, Biological Sciences, Pharmacology or a related field.
  • Prior wet lab experience in a biochemistry or biophysics-based lab and development of in vitro assays, SPR, NMR, or other biophysics techniques.

Nice To Haves

  • Background in biophysical techniques such as SPR, Mass spectrometry, NMR, X-ray crystallography.
  • Prior experience with membrane proteins (purification and/or assay development) is preferred.
  • Prior experience studying binding interactions between proteins and small molecules is preferred.
  • Excellent communication, collaboration, and interpersonal skills.
  • Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.

Responsibilities

  • Develop methods utilizing Surface Plasmon Resonance (SPR) to characterize interactions between challenging protein targets and small molecules.
  • Explore protein engineering and other biophysical techniques that can impact early chemical matter progression.
  • Obtain exposure to critical assays and strategies in early drug discovery.

Benefits

  • paid holiday time off benefits

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What This Job Offers

Job Type

Full-time

Career Level

Intern

Number of Employees

5,001-10,000 employees

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