2026 Summer Intern - BioAnalytical Sciences

Roche • South San Francisco, CA

18d • Onsite

About The Position

Our BioAnalytical Sciences (BAS) Department is a world-class bioanalytical center of excellence for novel strategies, technologies, and methods that enable the development of life-changing medicines. We foster an innovative and collaborative environment that values and recognizes a diversity of contributions. We are seeking a highly-motivated intern to join our team for the summer of 2026. The successful candidate for this laboratory-based position will work closely with our scientific team to develop a highly selective plug-and-play immunoaffinity enrichment, liquid chromatography-tandem mass spectrometry (IA LC-MS/MS) pharmacokinetic (PK) assay for a broad class of antibody-based biotherapeutic molecules. The project will utilize a range of high-throughput automation technologies to efficiently enhance sample preparation, paired with the latest state-of-the-art instrumentation. The ideal candidate is a detail-oriented scientist with a commitment to producing high-quality work, possessing strong general laboratory skills and a general understanding of liquid chromatography (LC), and tandem MS methods. This internship position is located in South San Francisco, on-site. The Opportunity The intern will focus on developing immunoaffinity (IA) LC-MS/MS based methods for assessing PK of biotherapeutic proteins from rat, cynomolgus monkey and human biological matrices. The intern will have access to and use targeted quantitative and proteomic workflows, such as HPLC coupled to Triple Quadrupole MS instruments and nano-LC coupled to a high-resolution MSn instrument. The intern will learn and perform automated, high-throughput sample preparation techniques. The intern will assess assay performance by conducting LC-MS/MS analyses and evaluate results using various data processing softwares. At the culmination of the internship, the intern will summarize and present their results at a Genentech intern poster session, as well BAS group and leadership team meetings. Program Highlights Intensive 12-weeks, full-time (40 hours per week) paid internship. Program start dates are in May/June 2026. A stipend, based on location, will be provided to help alleviate costs associated with the internship. Ownership of challenging and impactful business-critical projects. Work with some of the most talented people in the biotechnology industry.

Requirements

• Must be pursuing a PhD (enrolled student).
• Required Majors: Analytical Chemistry, Biochemistry, Chemical Engineering, Biology or related discipline.
• Fundamental knowledge and hands-on experience in LC-MS.

Nice To Haves

• Having a strong wet-lab experience is essential.
• Knowledge and experience handling biological samples and immunoaffinity workflows.
• Excellent communication, collaboration, interpersonal skills, and keen interest to learn.
• Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.

Responsibilities

• The intern will focus on developing immunoaffinity (IA) LC-MS/MS based methods for assessing PK of biotherapeutic proteins from rat, cynomolgus monkey and human biological matrices.
• The intern will have access to and use targeted quantitative and proteomic workflows, such as HPLC coupled to Triple Quadrupole MS instruments and nano-LC coupled to a high-resolution MSn instrument.
• The intern will learn and perform automated, high-throughput sample preparation techniques.
• The intern will assess assay performance by conducting LC-MS/MS analyses and evaluate results using various data processing softwares.
• At the culmination of the internship, the intern will summarize and present their results at a Genentech intern poster session, as well BAS group and leadership team meetings.

Benefits

• Intensive 12-weeks, full-time (40 hours per week) paid internship.
• Program start dates are in May/June 2026.
• A stipend, based on location, will be provided to help alleviate costs associated with the internship.

What This Job Offers

• Job Type: Full-time
• Career Level: Intern
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees