2026 Summer Intern - Analytical Development
About The Position
The Analytical Development team in Philadelphia is part of Roche’s Gene Therapy technical development function (PTCG). We accelerate the development of gene therapies by building the analytical roadmap used to assess product quality, safety, and efficacy. Through the detailed characterization of viral capsids, we provide the critical data needed to support regulatory approvals and deliver life-changing medicines to patients. We are seeking a curious and motivated co-op to join our team to advance the comprehensive molecular characterization of AAV gene therapy vectors. This internship position is located in Philadelphia, on-site.
Requirements
- Must be pursuing a Bachelor's Degree (enrolled student).
- Must be pursuing a Master's Degree (enrolled student).
- Required Majors: Chemistry, Biochemistry, Biotechnology, Pharmaceutical Sciences, or related fields.
- Practical experience with biochemistry related lab techniques and safety.
- Strong academic understanding of protein structure, chemistry, and Post-Translational Modifications (PTMs).
Nice To Haves
- Excellent communication, collaboration, and interpersonal skills.
- Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.
- Theoretical understanding or exposure to protein analytical methods, specifically Liquid Chromatograph, Mass Spectrometry, or capillary-based separation methods is a strong plus.
- Familiarity with gene therapy concepts or Adeno-Associated Virus (AAV) biology.
Responsibilities
- Gain hands-on experience with Mass Spectrometry (LC-MS) workflows—specifically intact mass analysis, PTM profiling, and peptide mapping—alongside other biochemical assays to characterize viral vector protein quality attributes.
- Work alongside Subject Matter Experts (SMEs) to learn advanced sample preparation techniques, assisting in the generation of study material, and the integration of data from complementary analytical methods.
- Analyze experimental data to assess structural features and capsid composition, contributing directly to the team's understanding of product quality.
- Assist in evaluating relationships between molecular product quality attributes and process performance.
- Document experimental protocols and results in laboratory notebooks and present technical findings to the research team.
Benefits
- Intensive 6 months, full-time (40 hours per week) paid internship.
- Program start dates are in May/June 2026.
- A stipend, based on location, will be provided to help alleviate costs associated with the internship.
- Ownership of challenging and impactful business-critical projects.
- Work with some of the most talented people in the biotechnology industry.
- paid holiday time off benefits
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What This Job Offers
Job Type
Full-time
Career Level
Intern
Number of Employees
5,001-10,000 employees
