Vice President and U.S. Squad Leader, Neurodegeneration (ND)

Roche • South San Francisco, CA

10d • Onsite

About The Position

Vice President and U.S. Squad Leader, Neurodegeneration (ND) Commercial Portfolio Organization (CPO) | Genentech Alzheimer's and Parkinson's diseases have stolen memories, mobility, and lives for decades. We are finally armed with the science to fight back. We are building a robust neurodegeneration pipeline. It includes our flagship Alzheimer's therapy, trontinemab, and key Parkinson's assets like prasinezumab. In addition, our Diagnostics colleagues have developed and are poised to commercialize ground-breaking blood based biomarkers for Alzheimer’s which will allow us to radically re-shape patient journeys and care models. But a pipeline does not save lives on its own. We need a commercial engine to put these medicines into the hands of patients. We are seeking a Vice President and U.S. Squad Leader for Neurodegeneration. You will build this engine. The Role You hold single-point accountability for the P&L, strategy, and successful commercialization of our entire U.S. neurodegeneration portfolio. You will report directly to the Senior Vice President of the Commercial Portfolio Organization (CPO) and sit on the CPO Leadership Team (CPOLT). You are not just launching drugs. You are building a new market. Treating neurodegeneration requires systemic changes in healthcare delivery. You will design the strategy and assemble the exact cross-functional Squad—including Medical, Marketing, Access, Field, and Operations—needed to execute it. You will also design and execute a novel commercialization model with our Roche Diagnostics colleagues to drive radical shifts in the way Alzheimer’s is identified and treated.

Requirements

• You bring a powerful blend of scientific depth and commercial agility. You understand the complex biology of neurodegeneration, and you know how to build a multi-billion-dollar business around it.
• A Builder: You have a proven track record of bringing new therapies to market, especially in disease areas requiring significant market shaping and diagnostic infrastructure.
• A Decisive Strategist: You make sound trade-off decisions. You know how to allocate budget and headcount across an expanding portfolio to maximize both revenue and patient reach.
• A VACC Leader: You are a Visionary, Architect, Catalyst, and Coach. You inspire teams to tackle impossible problems. You do not manage from the rearview mirror; you operate with speed to the need.
• A Cross-Functional Expert: You have demonstrated success uniting diverse teams—Sales, Marketing, Medical Affairs, Market Access, and Analytics—around a single, patient-focused goal.
• Bachelor’s degree required. An advanced degree (MBA, MD, PhD, or PharmD) is highly preferred.
• 15 or more years of commercial, medical, or overarching business leadership experience in the biotechnology or pharmaceutical industry.
• 10 or more years of people management experience, including a proven track record of leading senior leaders and guiding large, cross-functional matrix teams.
• Extensive experience launching products in the U.S. market. Direct experience in neurodegeneration (Alzheimer's, Parkinson's) or other highly complex specialty markets is strongly preferred.
• Demonstrated success in P&L management, portfolio prioritization, and resource allocation at scale.
• This role is based at our South San Francisco headquarters. The candidate must be willing to travel up to 40% to engage with field teams, key accounts, and global partners.

Responsibilities

• Build the ND Squad and Network: You will recruit, motivate, and lead a cross-functional network. You will define the required capabilities to win, from Key Account Managers targeting top-tier neurology clinics to specialized field teams focused on diagnostic pathways.
• Commercialize the Pipeline: You will lead the U.S. go-to-market strategy for our pipeline assets. Your immediate focus will be preparing the market for our Phase 1b/2a trontinemab readout and advancing our Parkinson's strategy.
• Shape the Healthcare Ecosystem: You will clear the bottlenecks that keep patients from care. You will direct strategies to build clinical infrastructure, establish precise diagnostic pathways (PET scans, blood biomarkers, and CSF tests), and expand site-of-care capacity.
• Enterprise Stewardship: You will represent the U.S. perspective in global R&D and pipeline investment decisions. You will partner seamlessly with Global Product Strategy (GPS), Product Development (PD), and Pharma Technical (PT) to ensure our medicines reach the U.S. market quickly and safely.
• External Leadership: You will act as Genentech’s primary spokesperson for neurodegeneration. You will build deep, trusted relationships with patient advocates, therapeutic area experts, payers, and policymakers.

Benefits

• Relocation assistance is available for this position.
• A discretionary annual bonus may be available based on individual and Company performance.
• This position also qualifies for the benefits detailed at the link provided below.

What This Job Offers

• Job Type: Full-time
• Career Level: Executive