Vertex Pharmaceuticals-posted about 18 hours ago
$26 - $50/Yr
Full-time • Intern
Hybrid • Boston, MA
5,001-10,000 employees

The Vertex Single Cell Genomics Co-Op program is a 6-month experiential training program for students currently working towards an advanced degree in Systems Biology, Developmental Biology, Stem Cell Biology, Biochemistry, Biological Engineering, Chemical Engineering, or other related fields. If you are passionate, collaborative, and growth-minded, a co-op at Vertex will help you gain meaningful experience in our analytical sciences functional areas and serve as a launchpad for your career. Please note that Vertex reviews applications on a rolling basis and reserves the right to close this job posting prior to the listed deadline. The co-op student's primary role is applying bioinformatics skills to interpretate bulk and single cell RNA sequencing data to deepen our understanding of the stem cell differentiation process, and monitor the differentiation progress. Specifically, they will use bioinformatics tools, such as Seurat or Scanpy, to map time course differentiation trajectory and identify potential correct and wrong trajectories of our process. Using the knowledge gained in this activity, the candidate will then nominate lists of genes to enable development of other RNA-based assays to closely monitor stem cell differentiation process. The co-op student will also assist in wet lab construction of single cell RNA sequencing libraries, and operation of Illumina sequencers.

  • Daily mapping of our differentiation process using available single cell RNA sequencing data.
  • A collection of wrong differentiation trajectories and a collection of potential failure modes identified by single cell RNA sequencing.
  • Lists of RNA targets to monitor correct and wrong differentiation trajectories.
  • Enrolled in a graduate program in Systems Biology, Computational Biology, Developmental Biology, Stem Cell Biology, Biochemistry, Biological Engineering, Chemical Engineering, or another related field
  • Analysis, visualization, and interpretation of next-generation sequencing (NGS) data.
  • Experience with Seurat, Scanpy, DESeq2 and other bioinformatics tools used for single cell RNA sequencing and bulk RNA sequencing data analysis is preferred.
  • Proficiency with R, Python, Linux systems, high-performance computing systems
  • Fundamental knowledge in developmental biology, stem cells and differentiation are preferred
  • Fundamental knowledge in sequencing library preparation and sequencer operation are preferred
  • A team-oriented growth mindset that welcomes feedback from others and supports other team members; strong collaboration skills to work across teams and functions
  • A positive attitude that enthusiastically tackles and overcomes challenges
  • Strong organizational and time-management skills to prioritize needs
  • Excellent presentation and communication skills, including the ability to tailor scientific content to audiences with different backgrounds
  • Legal authorization to work in the United States, now and in the future. Please note that Vertex does not provide sponsorship for internships or entry level roles within this part of the organization.
  • You must be enrolled in an advanced degree program if graduating before June 2026
  • You must be available to work full-time, 40 hours per week from January – June 2026
  • Experience with Seurat, Scanpy, DESeq2 and other bioinformatics tools used for single cell RNA sequencing and bulk RNA sequencing data analysis is preferred.
  • Fundamental knowledge in developmental biology, stem cells and differentiation are preferred
  • Fundamental knowledge in sequencing library preparation and sequencer operation are preferred
  • Free 24/7 onsite gym access and free access to group exercise classes
  • Subsidized commuter benefits- transit and parking
  • Provided meals—free breakfast daily!
  • Career development opportunities and events, including C Suite engagement
  • Social events—both intern-only and company-wide
  • Location-specific perks and extras!
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