US Head of Early Assets, CVRM Medical

AstraZeneca•Wilmington, DE

About The Position

At AstraZeneca we work together across global boundaries to make an impact and find answers to challenges. We do this with the utmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue outstanding medicines in new ways, combining our people’s outstanding skills with those of people from all over the globe. AstraZeneca holds an outstanding position in CVRM disease, with a range of differentiated medicines both on the market and in development, with an industry leading pipeline. The US Head of Early Assets, CVRM Medical is a critical strategic leadership position that reports directly to the VP Medical Cardiovascular Renal Metabolism (CVRM), within the BioPharmaceuticals Business Unit’s US Medical CVRM franchise. The candidate will work alongside their global counter parts to ensure adequate US input and involvement in our pipeline products that do not yet have dedicated local teams. This role will also work directly with local cross functional teams to build US product and disease area strategies and execution before dedicated teams are established. What you’ll do: Accountable for the development and execution of disease area and brand strategies and plans for early CVRM pipeline assets Act as the main US source of clinical and scientific knowledge for pipeline assets’ disease area, competitive landscape, clinical pathways, and evidence gaps Participate proactively in global and local conversations to ensure US medical input into global and local strategies Partner effectively and role‑model effective teamwork across the enterprise Act effectively as the key US point of contact for the Global Product Team (GPT) Provide the US viewpoint into global clinical trial strategy and study design Identify, develop, and maintain positive relationships with key external and internal collaborators Anticipate future trends and needs in the marketplace Participate as part of the US Medical CVRM LT to establish a team culture that encourages continued growth and recognition Ensure compliance with all AstraZeneca corporate policies Essential for the role: Sophisticated Scientific Degree (MBBS, PharmD, PhD, or MD) or equivalent education Medical/clinical/scientific expertise in Cardiovascular, Renal, Metabolic or related field 10+ years of experience in the pharmaceutical industry, ideally in Medical Affairs Strategic and innovative problem solver with executive presence Experienced team leader, with a track record of establishing high performance teams Proven record delivering results in a complex matrix environment, building capabilities, and leading large scale impactful medical initiatives. Experience launching a new product US Regulatory Strategy Knowledge/Experience, including new product approval, labeling requirements/negotiations Ability to flex between high level strategy and detailed tactics, as the need arises Confirmed ability to collaborate and build internal and external networks Persuasive oral and written communication skills, including the ability to develop and deliver impactful presentations Confirmed ability to collaborate with individuals of diverse experience and backgrounds, across varying functions, levels within the company, or external organizations, to effectively deliver on goals Strong intuition for business, with comprehensive understanding of the U.S. healthcare environment Date Posted 28-Jan-2026 Closing Date 27-Feb-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form. AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.

Requirements

Sophisticated Scientific Degree (MBBS, PharmD, PhD, or MD) or equivalent education
Medical/clinical/scientific expertise in Cardiovascular, Renal, Metabolic or related field
10+ years of experience in the pharmaceutical industry, ideally in Medical Affairs
Strategic and innovative problem solver with executive presence
Experienced team leader, with a track record of establishing high performance teams
Proven record delivering results in a complex matrix environment, building capabilities, and leading large scale impactful medical initiatives.
Experience launching a new product
US Regulatory Strategy Knowledge/Experience, including new product approval, labeling requirements/negotiations
Ability to flex between high level strategy and detailed tactics, as the need arises
Confirmed ability to collaborate and build internal and external networks
Persuasive oral and written communication skills, including the ability to develop and deliver impactful presentations
Confirmed ability to collaborate with individuals of diverse experience and backgrounds, across varying functions, levels within the company, or external organizations, to effectively deliver on goals
Strong intuition for business, with comprehensive understanding of the U.S. healthcare environment

Responsibilities

Accountable for the development and execution of disease area and brand strategies and plans for early CVRM pipeline assets
Act as the main US source of clinical and scientific knowledge for pipeline assets’ disease area, competitive landscape, clinical pathways, and evidence gaps
Participate proactively in global and local conversations to ensure US medical input into global and local strategies
Partner effectively and role‑model effective teamwork across the enterprise
Act effectively as the key US point of contact for the Global Product Team (GPT)
Provide the US viewpoint into global clinical trial strategy and study design
Identify, develop, and maintain positive relationships with key external and internal collaborators
Anticipate future trends and needs in the marketplace
Participate as part of the US Medical CVRM LT to establish a team culture that encourages continued growth and recognition
Ensure compliance with all AstraZeneca corporate policies