Translational NAMs Science & Technology Integration Director— Translational Safety & Risk Sciences

Amgen • South San Francisco, CA

82d • $240,284 - $280,634 • Hybrid

About The Position

Join Amgen's Mission of Serving Patients. At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Requirements

• Doctorate degree and 4 years of relevant scientific experience, or Master's degree and 7 years of relevant scientific experience, or Bachelor's degree and 9 years of relevant scientific experience.
• Recognized expertise in New Approach Methodologies (NAMs), including advanced in vitro models, quantitative systems pharmacology, or AI/ML-driven translational modeling.
• Demonstrated scientific leadership in developing, implementing, and integrating new technologies across the research continuum.
• Consistent track record of influencing portfolio decisions through data-driven, mechanistic insight.

Nice To Haves

• Ph.D. in Cell Biology, Molecular Biology, Pharmacology, Systems Biology, Biomedical Engineering, or a related field with 10 years of experience spanning drug discovery, translational research, or safety sciences.
• Experience mentoring and developing scientific staff and leading cross-functional or matrix teams.
• Strong external visibility through publications, consortium leadership, regulatory engagement, or scientific presentations.
• Exceptional communication and collaboration skills, with the ability to align diverse stakeholders and translate complex science into strategic impact.

Responsibilities

• Help redefine how translational science informs drug discovery and development through the integration of New Approach Methodologies (NAMs).
• Serve as a central catalyst for transformation within Translational Safety & Risk Sciences (TSRS).
• Ensure that state-of-the-art model systems, computational tools, and analytical frameworks are fully leveraged and implemented.
• Unite teams within TSRS and build strong partnerships across Research and other key groups within R&D.
• Lead the advancement and implementation of state-of-the-art NAMs within TSRS.
• Build bridges between TSRS wet and dry lab functions and key partners across Research.
• Develop and integrate pioneering 3D tissue models, organoids, micro-physiological systems, computational toxicology, and AI/ML-based modeling.
• Leverage QSP, PK/PD, and mechanistic data to build a cohesive framework linking model systems, biomarkers, and clinical endpoints.
• Lead internal and external collaborations to accelerate NAM validation and application.
• Apply NAMs-driven evidence to translational safety, pharmacology, and biomarker discovery.

Benefits

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts.
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan.
• Stock-based long-term incentives.
• Award-winning time-off plans.
• Flexible work models, including remote and hybrid work arrangements.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Industry: Chemical Manufacturing
• Education Level: Ph.D. or professional degree