About The Position

Assists with setting up and execution of experiments and support the validation of AAV gene therapies. May set up biochemical & cell-based assays to support production, identification, optimization, and characterization of AAV gene therapies. May analyze and present data to lead scientists in an organized and timely manner. Work within and support biology needs of discovery teams. Performs research and/or development in collaboration with others for projects. Makes detailed observations, analyzes data and interprets results with some supervision. Investigates, creates and develops new methods and technologies for project advancement. Obtains professional expertise through familiarity with scientific literature and educational tools. May participate in scientific conferences and contribute to scientific journals.

Requirements

  • BS/BA degree and some relevant experience preferred
  • General knowledge of AAV biology and/or protein engineering
  • Experience with molecular biology techniques such as PCR, digital PCR, gel electrophoresis, western blot/ELISA, plasmid design, cloning, and sequencing
  • Experience with cell culture in vitro techniques such as cell passage of adherent and suspension cells, sterile technique, media preparation, cell lysis, and material processing
  • Excellent critical analysis skills and ability to assess data and research findings outside of Neurocrine for application to new scientific projects
  • Advanced knowledge and demonstrated ability to work with a variety of laboratory equipment/tools
  • Ability to work as part of teams
  • Excellent computer skills
  • Excellent communication skills
  • Ability to meet multiple deadlines across a variety of projects/programs, with a high degree of accuracy and efficiency

Responsibilities

  • Performs experiments with some supervision in support of scientific activities and project goals involving cell and biochemical assays
  • Follows new methods and techniques and seeks out senior personnel for training and to discuss clarifications and explanations of methods and results
  • Generates complex bioinformatic data sets following SOPs, and assists in data analysis
  • Assists in maintenance of cell culture facilities, including growing cell cultures, cell banking and cleaning and stocking of equipment and rooms
  • Follows SOP's and organizes data for experiments conducted, and presents data to research team members
  • Complies with all SOP's, and safety and quality assurance standards at all times
  • May assist in research and support of Gene Therapy drug development
  • Other duties as assigned
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