Technical Development Staff Scientist

Genentech • Daly City, CA

102d • $180,700 - $335,500

About The Position

As part of Pharma Technical Development (PTD) our organization is committed to deliver the Pharma ambitions by bringing game-changing therapies from clinical phase I into the market to serve every patient, every day. Our core business is to develop safe, innovative and effective drugs using cutting edge technologies for manufacturing process (Drug Substance and Drug Product), clinical supply, formulation, device, packaging, and analytical development. Together with our partners, Global Biologics Bioprocess Development develops robust, efficient, and sustainable bioprocesses including Cell Line & Media Development, Cell Culture & Fermentation, and Purification Development. The Cell Culture Development US organization provides innovative technologies and strategic support for development and commercialization of Genentech and Roche’s biologic portfolio, including standard monoclonal antibodies as well as complex and modified proteins such as antibody drug conjugates and bispecific antibodies. The Roche/Genentech biological portfolio spans late stage research (LSR), preclinical, clinical, and initial marketing authorization. The department of Cell Culture and Bioprocess Operations (CCBO) within Genentech’s Pharma Technical Development (PTD) organization is seeking a highly experienced and self-motivated senior-level scientist to lead cell culture media development efforts for a diverse range of biological products. The ideal candidate for this role will have extensive cell culture media development experience and demonstrated strengths in fostering teamwork and collaboration with an inclusive mindset.

Requirements

• PhD (biological sciences, chemical engineering or related discipline) with 10+ years of relevant work experience OR BS/MS (biological sciences, chemical engineering or related discipline) with 14+ years of relevant work experience.
• Solid understanding of cell metabolism and tools for metabolic pathway analyses.
• Expertise in using computational methods, metabolic models, statistical design of experiments, –omics, and other current technologies to improve cell culture processes.
• Prior experience in media development for mammalian cell cultures.
• Prior experience in technology transfer and development of cell-based therapies is a plus.
• Demonstrated ability to lead and drive technical projects to completion through scientific rigor and strong organization skills.
• Proven track record of managing and developing highly productive technical teams with an inclusive mindset.
• Proven track record of building and maintaining strong relationships with partners, customers, and collaborators.
• Proven track record of excellent verbal and written communication through conference presentations and publications.

Responsibilities

• Develop chemically-defined cell culture media to meet different needs, including high-density cultures for biologics manufacturing, and cell-based therapies.
• Innovate, define strategies, and apply advanced technologies to improve cell culture performance and establish next-generation platform processes.
• Serve as primary in-house expert for state-of-the-art practice in media development.
• Provide technical leadership and strategic guidance to support technical/product teams, media preparation operations, raw material assessments, and supply chain updates.
• Guide, motivate, and develop staff in the Media and Process Group (MPG) within CCBO, with emphasis on defining their technical priorities and focus.
• Cultivate a lean mindset with focus on simplification and continuous improvement.
• Interface effectively within CCBO department and PTD, as well as with other internal Genentech/Roche organizations and external collaborators.
• Anticipate, identify, and resolve issues, with escalation and stakeholder communication where appropriate.
• Exert influence inside and outside the company through presentations, publications, and participation in meetings.

Benefits

• Relocation benefits are available for this position.
• A discretionary annual bonus may be available based on individual and Company performance.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees