Technical Associate I, Yaffe Lab

MIT • Cambridge, MA

6d

About The Position

TECHNICAL ASSOCIATE I , YAFFE LAB , Koch Institute for Integrated Cancer Research-Yaffe Lab , to work closely with several lab members and perform independent research using CRISPR-based screens for sensitization of tumor cells to signaling pathway inhibitors and chemotherapeutic drugs, combined with in vivo mouse tumor studies. Responsibilities include performing a broad range of basic laboratory experiments using standard techniques, including tissue culture techniques, CRISPR screening, maintaining mouse tumor and human PDX models, delivery of novel anti-cancer therapeutics into mice and target tumors, molecular cloning, immunoblotting, flow cytometry, and other biochemical/molecular assays; statistical data analysis; evaluating, designing, and revising research methods/procedures/techniques based on established objectives; and adjusting basic experimental protocols to ensure project completion in a timely fashion.

Requirements

• Bachelor’s degree in a relevant field
• two years of specialized lab experience (may include experience gained as an undergraduate)
• working knowledge of general laboratory practices and procedures
• experience with mouse cancer models, signal transduction biochemistry, and relevant molecular biology and cell culture techniques
• experience conducting and applying online research to projects
• excellent communication and interpersonal skills
• comfort analyzing, summarizing, and reporting results to researchers
• commitment to exceeding quality standards, providing exceptional services, and producing accurate and high-quality work
• meticulous attention to detail
• ability to follow safety procedures, maintain a safe work environment, and work independently and as part of a team

Nice To Haves

• Master’s degree in related field
• broad knowledge of the work done in the labs
• experience collaborating with a diverse group of researchers/trainees

Responsibilities

• performing a broad range of basic laboratory experiments using standard techniques, including tissue culture techniques, CRISPR screening
• maintaining mouse tumor and human PDX models
• delivery of novel anti-cancer therapeutics into mice and target tumors
• molecular cloning, immunoblotting, flow cytometry, and other biochemical/molecular assays
• statistical data analysis
• evaluating, designing, and revising research methods/procedures/techniques based on established objectives
• adjusting basic experimental protocols to ensure project completion in a timely fashion

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Number of Employees: 5,001-10,000 employees