Supply Chain Manager, Planning & Capacity

Amgen • Holly Springs, NC

2d • Onsite

About The Position

Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. SUPPLY CHAIN MANAGER (STRATEGY & CAPACITY PLANNING) What you will do Let’s do this. Let’s change the world. In this role, you will be responsible for leading strategy and capacity planning activities for the ANC (Amgen North Carolina) Drug Substance manufacturing site and will report within the ANC Supply Chain team. This role will be responsible for providing internal strategic consulting and capacity expertise to help ANC reach its full potential within the Amgen network, now and in the future. This role ensures accurate, forward-looking, and standardized capacity visibility to support Master Production Scheduling (MPS), Long Range Strategy (LRS), New Product Introductions (NPI), and commercial supply reliability. The position also supports the development, maintenance, and governance of DS capacity assumptions. The role ensures alignment with network DS planning standards and requirements while enabling site leadership to make informed, data-driven decisions regarding investments, risk mitigation, and operational trade-offs. This position has visibility across site and supply chain leadership and the Global Supply Chain network. This position will be located at the Holly Springs, North Carolina manufacturing site. Support business strategy assessment of multiple production plan scenarios to determine options, resource / capital requirements, risk and mitigation strategy, financial and supply implications with support of a cross-functional stakeholder team. Develop metrics and analytics tools to rapidly assess impact of pending changes for assessment. Lead end-to-end DS capacity modeling for the ANC site; develop and maintain capacity models incorporating available days, maintenance, run rate, float, success rate, and yield assumptions. Identify manufacturing bottlenecks and quantify impact to supply and service levels. Ensure ANC DS planning assumptions align with network standards for Available Days, Run Rate, Success Rate, and Yield. Maintain accurate planning parameters within Rapid Response and SAP planning systems. Develop scenario analyses to support LRS volume expansion, NPIs, capital investments, and risk mitigation strategies. Support governance forums tied to LRS and MPS cycles Provide executive-ready summaries to support site and network decision-making. Partner cross-functionally with Manufacturing, Engineering, Process Development, and Capital Projects to validate capacity assumptions. Support ramp-up planning for new products and assets, transitioning assumptions to demonstrated performance. Monitor success rate, run rate, and yield performance against targets and support continuous improvement initiatives. Develop dashboards and visualization tools to enhance transparency and executive decision-making. Build playbook and templates to ensure documented and easy to follow processes for role successors. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The Supply Chain professional we seek is a leader with these qualifications.

Requirements

• High school diploma / GED and 10 years of GMP Supply Chain / Manufacturing Planning experience OR Associate’s degree and 8 years of GMP Supply Chain / Manufacturing Planning experience OR Bachelor’s degree and 4 years of GMP Supply Chain / Manufacturing Planning experience OR Master’s degree and 2 years of GMP Supply Chain / Manufacturing Planning experience OR Doctorate degree

Nice To Haves

• In-depth understanding of biopharmaceutical manufacturing operations
• Experience with regulated environments (i.e., cGMP, GDP, OSHA)
• Strong understanding of upstream/downstream capacity modeling and bottleneck analysis
• Knowledge of yield modeling, run rate, float, and success rate assumptions
• Experience supporting LRS and MPS Planning Cycles
• Strong technical and data analytic skills and proficiency with AI, Databricks, Excel, SQL, Power BI and Tableau
• Supply Chain, Manufacturing Planning and/or Industrial engineering educational background
• Experience working with planning systems such as Rapid Response and SAP
• Operational Excellence and continuous improvement experience in regulated industry
• Good knowledge of Word, Excel, Smartsheet, Miro, and ability to work easily with new software
• Strong analytical, problem-solving, and cross-functional collaboration skills
• Ability to translate complex manufacturing data into strategic insights
• Excellent organizational, communication, and interpersonal skills
• Financial and business acumen

Responsibilities

• Support business strategy assessment of multiple production plan scenarios to determine options, resource / capital requirements, risk and mitigation strategy, financial and supply implications with support of a cross-functional stakeholder team.
• Develop metrics and analytics tools to rapidly assess impact of pending changes for assessment.
• Lead end-to-end DS capacity modeling for the ANC site; develop and maintain capacity models incorporating available days, maintenance, run rate, float, success rate, and yield assumptions.
• Identify manufacturing bottlenecks and quantify impact to supply and service levels.
• Ensure ANC DS planning assumptions align with network standards for Available Days, Run Rate, Success Rate, and Yield.
• Maintain accurate planning parameters within Rapid Response and SAP planning systems.
• Develop scenario analyses to support LRS volume expansion, NPIs, capital investments, and risk mitigation strategies.
• Support governance forums tied to LRS and MPS cycles
• Provide executive-ready summaries to support site and network decision-making.
• Partner cross-functionally with Manufacturing, Engineering, Process Development, and Capital Projects to validate capacity assumptions.
• Support ramp-up planning for new products and assets, transitioning assumptions to demonstrated performance.
• Monitor success rate, run rate, and yield performance against targets and support continuous improvement initiatives.
• Develop dashboards and visualization tools to enhance transparency and executive decision-making.
• Build playbook and templates to ensure documented and easy to follow processes for role successors.

Benefits

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible.

What This Job Offers

• Job Type: Full-time
• Career Level: Manager
• Education Level: High school or GED