Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance. Vaxcyte’s Summer Internship program offers students an opportunity to gain valuable work experience that complements their college curriculum with relevant hands-on work that can shape their future career pathing and interests. As a Protein Intern for Vaxcyte, you will work on a project as outlined below: Perform a literature review to understand cell-free protein synthesis (CFPS) and key principles of small-scale bioreactor operation. Support the design and execution of development studies aimed at establishing operating conditions in the Ambr 15 microbioreactor system for maintaining CFPS reaction setpoints (e.g., temperature, dissolved oxygen, and pH). Analyze experimental data to help design next studies or finalize operating conditions for 10 mL CFPS reactions. Document findings by drafting a work practice/SOP for running CFPS reactions in the Ambr 15 system. Present results and recommendations to the Protein team to support ongoing process development efforts. The Intern will learn and practice: Bioreactor operations and scale-down principles. Data analysis (process trends and analytical results). Electronic lab notebook (ELN) record keeping. Science communication. SOP/work practice writing skills.
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Career Level
Intern