Summer Intern, Bioassays

Arrowhead Pharmaceuticals•Madison, WI

10h•Onsite

About The Position

Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing. Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates. Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need. The Position The Bioassays Intern will support discovery research at Arrowhead Pharmaceuticals by contributing to a data-driven project aimed at improving the prediction of optimal cell lines for off-target assessment (OTA) screens. This internship will focus on building a comparative database linking RNA sequencing expression data with qPCR results to evaluate correlation and predictive value. The intern will gain hands-on experience in molecular biology techniques while working closely with scientists to generate data that may significantly accelerate bioassay timelines. This is an 11-week Summer Internship Program paying $21.00 per hour and requires full-time, onsite work five days per week at the designated location.

Requirements

Currently enrolled in a bachelor’s degree program at an accredited university or college and majoring in a scientific discipline such as Biochemistry, Biology, Chemistry, or Engineering.
Previous laboratory experience and familiarity with basic lab techniques.
Excellent verbal and written communication skills, including comfort presenting in group settings.
Strong problem-solving and organizational skills.
Proficiency in Microsoft Office applications.
Ability to lift up to 40 lbs.
Willingness and ability to spend 75% of the workday walking the facility and 25% at a desk.

Nice To Haves

Prior laboratory experience, with emphasis on genetics or molecular biology.
Familiarity with qPCR, RNA isolation, or gene expression analysis.
Strong attention to detail and interest in data-driven biological research.
Curiosity, enthusiasm for discovery science, and willingness to learn new approaches and techniques.

Responsibilities

Perform RNA isolations using good laboratory techniques
Prepare cDNA libraries for downstream analysis.
Perform real-time quantitative PCR (qPCR) assays.
Analyze and organize experimental data using Microsoft Excel.
Support cloning projects under the guidance of a research scientist.
Perform basic laboratory tasks including pipetting, solution preparation, and general bench work.
Present project updates in weekly group meetings.
Prepare final deliverables, including a scientific poster and a ~20-minute presentation summarizing project objectives, results, and learning.