Staff Software/Platform Engineer

Twist Bioscience•South San Francisco, CA

About The Position

We are seeking an experienced Staff Engineer to help maintain, evolve, and scale our multi-repository e-commerce platform and internal tooling. This role is ideal for a highly versatile engineer who is comfortable working across multiple technology stacks and designing, building, and operating scalable systems in a modern microservices-based architecture. As a Staff Engineer, you will serve as a technical leader developing and owning complex systems, influencing architectural decisions, and partnering closely with Product, Design, and DevOps to deliver reliable, high-quality solutions at scale. A strong systems-thinking mindset is essential to understand end-to-end workflows, cross-service interactions, and long-term system impacts.

Requirements

8+ years of professional software engineering experience with demonstrated impact on complex, distributed systems
Strong full-stack experience across modern frontend and backend technologies
Proficiency in systems thinking, including modeling system behavior, understanding trade-offs, and anticipating downstream effects of architectural decisions
Deep understanding of distributed systems, microservices patterns, and API design
Hands-on experience with AWS, including S3, EKS, WAF, Cost Explorer, and Bedrock
Strong communication skills with the ability to influence and collaborate across teams
Proven ability to balance hands-on development with architectural ownership and technical leadership

Nice To Haves

Experience integrating with Salesforce (SFDC) or PROS APIs is preferred

Responsibilities

Design, develop, and maintain frontend and backend systems across multiple repositories
Apply systems thinking to reason about end-to-end architecture, dependencies, failure modes, scalability, and long-term maintainability
Build responsive, performant user interfaces using React and TypeScript
Design, implement, and maintain RESTful APIs using Java, Python, and Node.js
Create and maintain API documentation using Swagger/OpenAPI
Develop and operate containerized services using Docker and deploy on Kubernetes (EKS)
Configure, maintain, and optimize CI/CD pipelines (Drone CI, Jenkins, Spinnaker)
Monitor system health, performance, and reliability using logging, metrics, and observability tools
Debug production issues and lead root cause analysis across distributed systems
Integrate and support third-party systems, including payment platforms (e.g., Stripe)
Collaborate cross-functionally with Product, Design, and DevOps to deliver end-to-end solutions
Enforce best practices for Git workflows, code reviews, and release management
Define and uphold microservices principles, including service boundaries, scalability, and system integrations