Precision Neuroscience-posted 4 months ago
$160,000 - $195,000/Yr
Full-time • Mid Level
Onsite • Boston, MA

Precision Neuroscience is building a next-generation brain–computer interface (BCI) to heal and empower millions of people living with neurological conditions. Our first product, Layer 7, is designed to help people with severe paralysis operate digital devices using only their thoughts—opening up new possibilities for daily life. Our team brings together experts in neurosurgery, AI and machine learning, microfabrication, electrical engineering, clinical science, and more. We combine deep technical rigor with a people-first mindset to turn breakthrough research into real-world medical solutions. As a Precision employee, you’ll join one of the fastest-moving and best-capitalized companies in the emerging field of brain–computer interfaces. Since our founding in 2021, we have raised more than $180 million, advanced our technology through validation, and initiated human trials with leading hospitals across the country. Our Values: Build for Human Impact ‧ Do No Harm ‧ Innovate with Urgency ‧ Sharp Minds, Open Ears ‧ Lead the Way We are seeking a highly experienced and detail-oriented Staff Scientist, Preclinical Surgical Research, to lead the design, execution, and analysis of preclinical animal studies at our Massachusetts-based Contract Research Organization (CRO). This is a senior-level, cross-functional role central to our scientific, technical, and regulatory efforts. The ideal candidate will bring deep large animal surgical expertise, scientific rigor, and operational leadership to the development of innovative neurosurgical and implantable systems. This position will be based in our Boston office. We are unable to consider remote workers or people not currently based in the United States who do not have employment authorization.

  • Design and execute preclinical animal studies to evaluate medical device systems and answer key scientific, technical, and regulatory questions. Define study objectives, endpoints, and methodology in alignment with R&D and regulatory strategy.
  • Lead the drafting, refinement, and execution of surgical protocols aligned with experimental goals, animal welfare standards, and regulatory requirements. Maintain strict version control and support protocol review and approval processes (e.g., IACUC, GLP).
  • Coordinate closely with R&D, Regulatory, and Quality teams to ensure that studies are designed and conducted to support system-level verification and validation (V&V), meet regulatory submission needs, and withstand technical and scientific scrutiny.
  • Perform and oversee complex surgical procedures, with an emphasis on large animal models. Ensure procedural consistency, sterility (where required), and surgical quality across studies.
  • Manage day-of-study execution, including experimental setup, surgical logistics, team coordination, and intraoperative troubleshooting.
  • Collect, analyze, and interpret experimental data to extract meaningful insights, inform system development, and support formal reporting. Collaborate with internal stakeholders to contextualize results within broader product development.
  • Own inventory and procurement of all experimental and surgical supplies, ensuring readiness and compliance with procedural requirements.
  • Maintain meticulous surgical and experimental records, including intraoperative observations, procedural deviations, and postoperative outcomes.
  • Lead cross-functional debriefings after surgical sessions and produce detailed technical reports to inform design iteration and future studies.
  • Organize and lead planning meetings for in vivo experiments, ensuring timely decisions, clear documentation, and alignment across research, veterinary, and operational stakeholders.
  • Minimum of 5 years of experience conducting and analyzing in vivo surgical research, preferably with large animal models.
  • Strong experience in the design and execution of preclinical studies supporting medical device development.
  • Familiarity with GLP principles, V&V requirements, and regulatory expectations related to animal studies.
  • Proven ability to work across functions to translate experimental findings into design, risk, and regulatory documentation.
  • High proficiency in sterile surgical technique, operating room setup, instrumentation, and procedural execution.
  • Demonstrated excellence in data analysis, technical documentation, and communication with cross-functional teams.
  • Outstanding organizational skills and attention to detail.
  • Advanced degree (MS, PhD, DVM) in biological sciences, biomedical engineering, veterinary science, or a related field.
  • Direct experience conducting complex surgeries in large animal models (e.g., pigs, non-human primates).
  • Prior involvement in GLP or regulatory-submission-enabling preclinical studies.
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