Staff Scientist - Nephrology

Washington University in St. Louis • St. Louis, MO

3d • $48,000 - $86,900 • Onsite

About The Position

The Mahjoub laboratory studies the role of the cell cytoskeleton in regulating cell physiology, tissue formation, and organ development, with specific focus on microtubule-based organelles called centrosomes and cilia. Our aim is to determine the consequences of centrosome-cilia defects in the development of human ciliopathy syndromes, with specific focus on renal and pulmonary ciliopathies. This specific project involves characterization of centrosome defects and how they cause cystic kidney disease. The experiments involve multiple systems and tools including primary cell cultures and organoids, transgenic mice, advanced microscopy techniques (Superresolution, ultrastructure expansion, electron, and live-cell imaging), as well as standard molecular and biochemical laboratory methods. Designs research protocols. Assists in developing and conducting research projects, including experiment design, data analysis and documentation of experiment results.

Requirements

• Master’s degree or combination of education and/or experience may substitute for minimum education.
• Laboratory Operations (3 Years)

Nice To Haves

• Extensive experience using preclinical mouse models of human disease. This includes handling mice, genotyping/phenotyping, drug administrations in mice, etc.
• Isolation of organs, tissues and other samples from mice, and analysis by these specimens by histology and other methods.
• Prior training in mammalian cell culture and/or organoid systems.
• Experience with immunofluorescence microscopy.
• Ph.D. - Doctor of Philosophy
• Analytical Problem Solving
• Communication
• Computer Literacy
• Data Analysis
• Data Interpretations

Responsibilities

• Following instructions and discussions with the principal investigator, designs research protocols, including developing procedures for the collection, verification and management of data.
• Assists with grant preparation and reporting.
• Performs complex statistical analysis of data collected and writes interpretative reports.
• Verifies the correctness of the data submitted and makes recommendations based on these analyses.
• Documents research topics and prepares and submits papers based on research work to publications and committees for publication or presentation to peers.
• Solves practical problems relating to difficulties with equipment or test subjects.
• Suggests technical or procedural improvements in testing methods.
• Conducts literature searches related to research project.
• Performs other duties as assigned.

Benefits

• Up to 22 days of vacation, 10 recognized holidays, and sick time.
• Competitive health insurance packages with priority appointments and lower copays/coinsurance.
• Take advantage of our free Metro transit U-Pass for eligible employees.
• WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.
• Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more!
• We offer 4 weeks of caregiver leave to bond with your new child. Family care resources are also available for your continued childcare needs. Need adult care? We’ve got you covered.
• WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level