Sr. Scientist, Radiopharmaceutical Development

Bristol Myers Squibb
99d$131,028 - $158,775

About The Position

Working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible. Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. RayzeBio, a Bristol Myers Squibb company, is a dynamic biotechnology company headquartered in San Diego, CA. The company is focused on improving survival of people with cancer by harnessing the power of targeted radioisotopes. RayzeBio is developing innovative drugs against targets of solid tumors. Led by a successful and experienced entrepreneurial team, RayzeBio aims to be the global leader in radiopharmaceuticals. The Sr. Scientist, Radiopharmaceutical Development is a leading contributor in the design, development, and advancement of RayzeBio’s radiopharmaceutical programs.

Requirements

  • BSc +7 years, MSc + 5 years or PhD +3 years in Chemistry, Radiochemistry, Pharmaceutical Sciences, or related field with relevant industry experience, including significant work with radioactive materials, novel isotopes, and chelator chemistry.
  • Demonstrated expertise in radiochemical synthesis, purification, formulation, and analytical techniques.
  • Proven track record of innovation in radiopharmaceutical development, including novel isotope and chelator research.
  • Deep familiarity with federal and state regulatory requirements and safety protocols for radioactive materials.

Nice To Haves

  • Advanced experience developing stable radiopharmaceutical formulations with targeted attributes such as extended shelf-life, radiochemical purity, and enhanced bio-distribution.
  • Hands-on expertise with commercial and custom radiopharmaceutical manufacturing and analytical equipment systems, including automation platforms, radioHPLC, radioTLC, gamma counters, dose calibrators, hot cell manipulators, and advanced gamma spectroscopy.
  • Extensive experience with a broad spectrum of radioactive materials for both diagnostic and therapeutic applications.
  • Strong professional ethics, integrity, and ability to maintain confidential information.
  • Outstanding written and verbal communication skills, with the ability to influence and communicate effectively across all levels, including executive leadership.
  • Proactive, innovative thinker who thrives in a fast-paced, multi-disciplinary industrial environment.
  • Demonstrated ability to manage complex research projects and mentor junior staff.

Responsibilities

  • Drive CMC process development and optimization for clinical drug products, including formulation lock and robust process definition, ensuring scalability and compliance with regulatory standards.
  • Lead the transfer of advanced radiopharmaceutical processes and technologies to internal and external manufacturing sites, including the Indianapolis facility and CDMO partners.
  • Oversee the development, operation, and maintenance of radiochemistry laboratory infrastructure, ensuring readiness for translational activities from preclinical through clinical phases.
  • Foster collaborative relationships with discovery scientists, external academic partners, and CDMOs to address complex scientific questions and pursue joint research efforts.
  • Independently design and execute advanced radiochemistry and radiolabeling experiments, with a special focus on novel radioisotope and chelator development to enable new classes of radiopharmaceuticals.
  • Serve as a subject matter expert in radiopharmaceutical production processes, quality control, and advanced analytical methodologies.
  • Direct research into the identification, synthesis, and characterization of novel isotopes and chelators to enhance therapeutic and diagnostic radiopharmaceutical properties.
  • Ensure strict adherence to radiation safety protocols, federal and state regulations, and internal guidelines for handling radioactive materials; promote a culture of safety-first and regulatory compliance.
  • Interpret complex experimental data, draw scientifically rigorous conclusions, and communicate findings in technical reports, regulatory documentation, and presentations for internal and external stakeholders.
  • Manage and prioritize research projects, oversee third-party vendors, and mentor junior scientists and associates.
  • Draft and review CMC sections for regulatory submissions, SOPs, and comprehensive development reports.

Benefits

  • Medical, pharmacy, dental and vision care.
  • Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP).
  • Financial well-being resources and a 401(K).
  • Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support.
  • Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two (2) paid days to volunteer, sick time off, and summer hours flexibility.
  • Parental, caregiver, bereavement, and military leave.
  • Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources.
  • Other perks like tuition reimbursement and a recognition program.

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What This Job Offers

Job Type

Full-time

Career Level

Senior

Education Level

Ph.D. or professional degree

Number of Employees

5,001-10,000 employees

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