Sr. Scientist II, Autoimmunity

Tonix Pharmaceuticals • Frederick, MD

12d • Onsite

About The Position

Tonix is seeking a highly motivated and innovative Senior Scientist II with a background in immunology with demonstrated expertise in Autoimmunity to contribute to research and development across our growing immunology portfolio. This is an excellent opportunity to directly participate and obtain exposure to the end-to-end product development process including early-stage therapeutic discovery, nonclinical safety and pharmacological evaluation, cGMP manufacturing and clinical evaluation. The candidate will have a Ph.D. or M.D./Ph.D. in a relevant field, a strong record of productivity, and experience working in an interdisciplinary team environment. The position is located at the Tonix Research and Development Center (RDC) which is the innovation and development arm of Tonix Pharmaceuticals. The RDC houses state-of-the-art equipment (e.g., high content imaging, mass spectrometry, spectral flow cytometry, in-vivo imaging, multi-parallel bioreactors, etc.) and is responsible for development of efficient and cutting-edge treatment methods for various diseases including infectious diseases, oncology, and other indications. This position will require an in-depth knowledge of in-vivo immunology with autoimmune models; will involve organizing and implementing complex research plans, developing methods of testing, data collection and analysis; and will involve writing reports containing descriptive, analytical, and evaluative content. The duties will also require the exercise of independent discretion and judgment in carrying out research activities within the predetermined research scope. Experience in the composition of scientific publications, research program technical reports, and research grants is required.

Requirements

• Ph.D., or equivalent doctoral degree
• Strong accomplishment record demonstrating the ability to perform independent, high-quality, creative, and impactful research in the field of application of viral vectors as vaccines against deadly pathogens and antibody or protein design and discovery
• Ability to generate hypothesis to test ideas, use the data set to evaluate hypothesis, and design new studies
• Ability to apply multiple cutting-edge techniques for immunological studies, such as high-content imaging, microscopy, and cell-based screening
• Ability for minimal travel
• Dedicated team player who can withstand the high demands of a fast-paced environment
• Excellent written and verbal communication skills are essential
• Strong planning and organizational skills
• Comfortable working independently with minimal supervision
• Highly organized, results-driven, problem solver, and collaborator
• Demonstrated ability to perform the essential duties of the position with or without accommodation

Responsibilities

• Development of robust and diverse in-vivo autoimmune models to support in-depth studies to assess mechanisms of action and efficacy.
• Conduct independent and original research supporting the Tonix portfolio and RDC mission
• Develop novel methods and assays to contribute to the RDC research pipeline
• Establish in-vitro and ex-vivo models to support evaluation of Immunotherapeutics against diverse disease conditions (e.g., autoimmunity, oncology)
• Collection, analysis, and evaluation of data
• Interpret data, make decisions, and conduct troubleshooting on related technical issues
• Preparation of scientific presentations, reports, manuscripts, and grant proposals
• Design, optimize, and standardize in-vivo, ex-vivo and in-vitro autoimmune models ensuring consistent reliability and reproducibility of screening outcomes.
• Establish methods to interrogate in-depth immunological pathways using multi-parameter spectra flow cytometry, in-vivo imaging and contemporary molecular approaches.
• Provide scientific expertise in cell-based, molecular, and biochemical assays, while ensuring rigorous experimental data analysis.
• Independently troubleshoot, problem-solve, and execute experiments, while effectively incorporating feedback and adapting to evolving project needs.
• Work cross-functionally in a matrix environment, partnering with project and functional teams to drive research objectives forward.
• Participate in cross-functional project teams, proposing innovative discoveries and optimization strategies that align with industry’s best practices.
• Uphold company mission and values, emphasizing accountability, innovation, integrity, quality, and teamwork.
• Support special projects and business initiatives as needed to contribute to Tonix's broader corporate strategy.

Benefits

• Medical, Dental & Vision Insurance, Basic and Voluntary Life and AD&D Insurance, Short- and Long-Term Disability Insurance, Flexible Spending Accounts, Health Savings Account, and Employee Assistance Programs
• Pet Insurance
• Retirement Savings 401k with company match and annual discretionary stock options
• Generous Paid Time Off, Sick Time, & Paid Holidays
• Career Development and Training

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree