Sr. Manager, Manufacturing Sciences & Technology (MSAT)

Codexis Inc • Redwood City, CA

3d • Hybrid

About The Position

The is responsible for and will be based in Blank city, Remote or Hybrid role. If any of the below describes you, we would love to meet you!

Requirements

• Experience with E. coli–based protein expression and purification.
• Prior involvement with CDMOs, including tech transfer and manufacturing oversight.
• Experience supporting clinical or commercial manufacturing deviation closures and regulatory submissions.
• Familiarity with enzyme manufacturing platforms or biologics CMC activities.

Responsibilities

• Lead the tech transfer of enzyme manufacturing processes into internal manufacturing suites and external partner facilities.
• Provide technical leadership across the product lifecycle, including process fit-to-plant assessments and manufacturability risk scoring.
• Drive scale-up activities and continuous process improvements to enhance yield, robustness, and maintain critical quality attributes.
• Serve as a subject matter expert to internal teams and CDMOs during process design, change control, and technical strategy execution.
• Provide on-the-floor technical support during critical manufacturing operations, including first-in-series runs.
• Oversee batch execution and support disposition activities ensuring compliance with ISO requirements.
• Lead real-time troubleshooting for equipment and process deviations to minimize downtime and ensure production continuity.

Benefits

• Medical, Dental and Vision Insurance
• Basic Life, AD&D, Short- and Long-Term Disability Insurance
• 401k with Company Match up to 4%
• Company Equity
• Generous Paid Time Off including 18 Company Holidays (with a summer and winter shutdown), Vacation, and Wellness Time
• Annual Lifestyle Account for reimbursement of fitness programs, equipment and more
• Employee Stock Purchase Program (ESPP)
• Flexible Spending Accounts (Commuter/Parking, Dependent Care & Healthcare)
• Student Debt Program (Company Contribution to Loans)
• Mental Health Wellness Program
• Subsidized onsite lunch program
• Onsite Gym Facilities
• Paid Parental Leave
• And More!

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: No Education Listed