Uncover a remarkable opportunity at Thermo Fisher Scientific Inc. to push global advancements in health, cleanliness, and safety as a Sr. IT Program Manager in Waltham. Become a part of our elite team, guiding ambitious IT projects that enhance quality, compliance, and supply chain operations within our Contract Development and Manufacturing Organization (CDMO). Argument Development & Case Creation Collaborate with business leaders to determine opportunities where technology provides measurable business value. Develop and present cases justifying investments by outlining the value, benefits, and resource requirements. Translate strategic goals into actionable IT roadmaps that support growth, scalability, and regulatory compliance. Support portfolio governance and prioritization discussions through data-driven analysis. Financial Oversight Manage program budgets, forecasts, and capital/operating expense planning. Monitor and report financial performance, ensuring accountability and transparency. Identify cost optimization and efficiency opportunities within vendor and system portfolios. Provide variance analysis and investment recommendations to senior leadership. Vendor & Partner Management Lead the selection, contracting, and performance oversight of technology vendors and service providers. Negotiate statements of work (SOWs) and service-level agreements (SLAs) in collaboration with Procurement and Legal. Monitor vendor delivery, quality, and compliance performance against expectations. Champion positive relationships that drive innovation and operational excellence. Quality, Compliance & Inspection Readiness Ensure all IT programs meet global regulatory and validation standards (21 CFR Part 11, GxP, GAMP 5, EU Annex 11). Maintain ongoing inspection readiness by ensuring complete validation documentation and traceability. Partner with Quality and Compliance teams to prepare for internal and external audits. Represent IT during inspections and drive timely remediation where vital. Systems & Integration Manage the incorporation and enhancement of essential platforms like ERP, MES, QMS, LIMS, and SCM systems. Ensure system development aligns with data integrity, cybersecurity, and infrastructure standards. Collaborate with architects and functional leaders to enable process harmonization and scalability. Thank you for your interest as you consider starting a new career journey with us. As the world leader in serving science, our colleagues develop critical solutions through innovation—and build rewarding careers. Discover their extraordinary stories and connection to our Mission to enable our customers to make the world healthier, cleaner and safer. Their work is a story of purpose. What story will you tell? Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue of more than $40 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, increasing productivity in their laboratories, improving patient health through diagnostics or the development and manufacture of life-changing therapies, we are here to support them. Our global team delivers an unrivaled combination of innovative technologies, purchasing convenience and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon and PPD. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Thermo Fisher Scientific is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, creed, religion, color, national or ethnic origin, citizenship, sex, sexual orientation, gender identity and expression, genetic information, veteran status, age or disability status.