Sr Director Medical Affairs, Pipeline Lead

Ultragenyx Pharmaceutical

1d•Remote

About The Position

ultradedicated – Your biggest challenges yield rare possibilities Ultragenyx is seeking a dynamic and experienced leader to join the Global Medical Affairs team with responsibility for the pipeline portfolio. The Sr. Director, Pipeline Lead will provide strategic early medical affairs leadership across multiple early-stage assets in our neurology and inborn errors of metabolism portfolios, including, for example, GNE Myopathy, Creatine Transporter Deficiency, Wilson’s Disease, and Ornithine Transcarbamylase Deficiency. This role requires an adaptable leader willing to take a “hands on” approach in their work and who is comfortable working in a fast-paced intellectual environment.

Requirements

Advanced medical/scientific degree (MD, DO, PhD, PharmD) (required)
Minimum 7 years of experience in Medical Affairs (required); global experience is strongly preferred
Proven track record in pipeline strategy, evidence generation, and external engagement
Experience and comfort operating across early-phase development programs spanning multiple disease areas
Strong collaboration and stakeholder management skills; adept at functioning in a highly matrixed environment
Recognized scientific authority with the ability to engage in advanced scientific and clinical discussions with both internal and external experts
High aptitude for attention to detail, commitment to high-quality work, and a sense of passion and urgency to achieve goals and improve the lives of patients
Highly analytical and strategic thinker with the ability to identify interdependencies, consider medical implications, and understand the broader goals of a program
Excellent communication skills, with the ability to effectively articulate scientific and strategic concepts in both written documents and verbal presentations
Travel estimated up to 15%

Responsibilities

Provide early medical affairs leadership to assigned programs, serving as an active core member of the Program Team and decision-making sub-teams, and contributing to the progression of program milestones
Demonstrate and apply deep rare disease expertise across assigned programs, actively building and maintaining a global network of therapeutic area experts. Lead insight-generation activities, including scientific advisory boards and steering committees that inform program strategy
Lead the development of an aligned early-stage Integrated Evidence Generation Strategy for assigned programs, incorporating real world evidence generation, ensuring plans are strategically designed and executed to establish a robust foundational scientific evidence base
Lead proactive competitive landscape assessments and translate emerging science and therapeutic area dynamics into strategic recommendations for asset positioning
Establish and lead the Global Medical Sub Team(s), and drive the development and implementation of the medical strategy for assigned pipeline programs, aligned with program objectives and through close collaboration with global medical functions and regional medical leads
Partner with scientific and medical communications to guide development of the end-to-end scientific communication platform, including the global scientific narrative, ensuring a consistent external global scientific education strategy
Ensure timely and effective data dissemination by leading publication strategies, congress planning, and scientific education initiatives
Provide deep disease area and product expertise, ensuring accurate and consistent communication of clinical and scientific data, including sign off in review committees
Provide guidance, tools, and high-quality compliant training to US field and regional medical affairs teams to elevate consistent scientific exchange, and other internal teams as needed
Collaborate effectively with clinical development, HEOR, diagnostics, scientific and medical communications and publications, regulatory, market access, commercial, training, and patient advocacy to influence strategic decision making and advance program initiatives