Sr Associate Scientist I or II, GPCR Biology
About The Position
We are seeking a highly motivated and experienced Senior Associate Scientist I/II to join the GPCR Biology group and advance our core mission of accelerating small molecule drug discovery programs at Iambic Therapeutics. The successful candidate will have a proven track record of supporting in vitro cell-based assays to advance pre-clinical projects. The candidate will work closely with a cross-functional team that integrates machine learning, medicinal chemistry, analytical technology and biology to revolutionize small-molecule therapeutics design and discovery. This role is based at our San Diego headquarters.
Requirements
- Bachelor's or master's degree in biochemistry, pharmacology, cell biology, or other related scientific areas with a minimum of 3-5 years of industry experience
- Hands-on experience with traditional and innovative screening methodologies for GPCRs, as well as concepts related to GPCR signaling and trafficking highly preferred
- Demonstrated scientific rigor with proven ability to critically evaluate data, and think independently and creatively in developing and testing new scientific hypotheses
- Hands-on experience in cell biology and routine biological assays, including cell culture, HTRF and reporter gene cell-signaling assays, and imaging assays
- Familiarity with HTS screening methodology is highly desirable
- Excellent oral and written communication skills is required
- Highly motivated to work in a cross-functional team setting
- Flexibility and ability to quickly learn new skills and knowledge on the job
- Experience with design and implementation of in vivo models in coordination with CROs is highly desirable
Nice To Haves
- Hands-on experience with traditional and innovative screening methodologies for GPCRs, as well as concepts related to GPCR signaling and trafficking highly preferred
- Familiarity with HTS screening methodology is highly desirable
- Experience with design and implementation of in vivo models in coordination with CROs is highly desirable
Responsibilities
- Work closely with the Biology group to independently conceptualize, design and conduct in vitro studies aimed at supporting hit to lead medicinal chemistry efforts targeting GPCRs
- Independently manage CRO scientists in the design, development, and implementation of in vitro assays for the advancement of GPCR projects
- Execute weekly cell-based assays to screen/evaluate small molecule compounds in coordination with Biology, Chemistry, and Compound Management groups
- Interpret and analyze scientific data and work with cross functional teams to QC/communicate data in a timely manner
- Present experimental results/updates at team meetings
- Contribute to the management of the biology laboratory
Benefits
- We offer industry leading competitive pay, company paid healthcare, flexible spending accounts, voluntary life insurance, 401K matching, and uncapped vacation to our team.
- We are in a brand-new state-of-the art facility in beautiful San Diego with an onsite gym, dining, and easy access to great places to live and play.
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Industry
Professional, Scientific, and Technical Services
Number of Employees
51-100 employees
