Sr. Associate Scientist, Antibody Discovery

Prellis Biologics • Berkeley, CA

337d

About The Position

Prellis Biologics uses proprietary technology to 3D print lymph node organoids, which we are using to generate invitro human lymph node cocultures for generating antigen-specific B-cells. We are seeking a Senior Associate Scientist, Antibody Discovery to join our Antibody Discovery team. In this role you will be supporting high-throughput antibody discovery efforts, particularly using primary cell co-culture approaches. The ideal candidate will have a strong background in molecular biology and cell culture work, with significant experience in supporting end-to-end antibody discovery campaigns.

Requirements

• B.S in Molecular Biology, Immunology, Biotechnology, or related life science field with 4+ years of experience, or M.S. with 2+ years of relevant experience.
• Strong proficiency in maintaining primary cell co-culture systems is required.
• Proficiency in Flow Cytometry workflows and single cell sorting for sequencing.
• Experience with FlowJo or comparable analysis software.
• Strong organizational and time management skills to contribute to multiple projects in a fast-paced environment.
• Excellent communication skills and ability to document and present experimental results.

Nice To Haves

• Strong experience in single B-cell antibody discovery workflows with an end goal of identifying novel therapeutic candidates.
• Prior experience with operating SONY MA900 cell sorters and MACSQuant analyzers.
• Thrive in collaborative environments and are open to a mentorship role within the team.

Responsibilities

• Perform high-throughput cellular biology techniques, including but not limited to, cell culture, Flow Cytometry, Fluorescence-activated cell sorting (FACS), and ELISPOT.
• Set up and maintain primary cell co-cultures using aseptic techniques.
• Develop, troubleshoot, and drive protocol optimization for enhanced efficiency and increased throughput.
• Develop and optimize automation protocols for improved efficiency in molecular and cellular assays.
• Collaborate with cross-functional teams in a fast-paced, matrixed environment.
• Maintain accurate records of experiments, analyze data independently, and present results in team meetings.

What This Job Offers

• Career Level: Mid Level
• Industry: Professional, Scientific, and Technical Services
• Education Level: Bachelor's degree