Site Contracts Manager (Sponsor Dedicated /Remote – US Based)

Syneos Health • Saldias, OH

5d • Remote

About The Position

Site Contracts Manager (Sponsor‑Dedicated /Remote – US Based) Are you a contracts expert who thrives on navigating complexity, building strong site partnerships, and driving timelines forward? Syneos Health is seeking a Site Contracts Manager to support a sponsor‑dedicated program focused on high‑impact Pharma & Vaccine studies. If you’re energized by problem‑solving, negotiation, and leading projects across multiple therapeutic areas—especially oncology—we’d love to meet you. About the Role: As a Site Contracts Manager, you’ll serve as a strategic expert responsible for negotiating and managing US site budgets and clinical trial agreements. You’ll collaborate closely with internal teams, external stakeholders, and major academic institutions to craft robust contracts that support operational excellence while minimizing risk. This role is perfect for a communicator, leader, and negotiator who’s ready to hit the ground running and make an immediate impact.

Requirements

• 3+ years negotiating budgets and contracts from templates
• Direct experience negotiating with large academic institutions
• Ability to juggle priorities, lead projects, and deliver results under tight timelines
• Strong understanding of clinical study protocols, timelines, and site‑related milestones (e.g., SIV)
• Bachelors degree

Nice To Haves

• 5+ years of site contracts and study start-up (SSU) experience within a global CRO or pharmaceutical sponsor environment, including ownership of multi-country studies.
• Demonstrated expertise negotiating site CTAs and investigator budgets, including direct interaction with sites, sponsors, Site Contract Service Centers, and Legal teams.
• Strong experience drafting and managing site-specific CTAs from country or global templates and ensuring alignment with sponsor MSAs and country requirements.
• Proven ability to manage contract amendments and protocol-driven changes, maintaining compliance with timelines, quality standards, and documentation requirements.
• Experience serving as an escalation point for complex contract, budget, or process issues, with a track record of proactive risk identification and resolution.
• Hands-on experience with SSU tracking systems and contract repositories, including real-time milestone tracking and metadata management.
• Demonstrated leadership in training and mentoring junior staff, including contribution to SOPs, WIs, templates, and internal training materials.
• Experience supporting business development activities, such as proposal development, bid defenses, or sponsor-facing meetings.
• Oncology & respiratory therapeutic area experience
• Prior experience with pharma
• Strong project management skills and comfort leading cross‑functional efforts

Responsibilities

• Budgeting & Template Development Create templates and study‑specific budget language for Pharma & Vaccine clinical trials. Develop and refine templates to support consistency, compliance, and strategic study needs.
• Contract Negotiation & Risk Management Lead direct negotiations with large academic institutions and other critical stakeholders. Draft and finalize clinical trial agreements that balance business objectives with legal and operational protections. Conduct due diligence checks—such as FMV assessments and site justification reviews—when initial offers are declined. Determine when requests require budget or language escalation and secure appropriate approvals.
• Project Leadership & Delivery Prioritize and lead multiple contracting projects across several therapeutic areas (oncology & respiratory experience strongly preferred). Proactively escalate risks, timeline impacts, or delays that could affect CTA execution.
• Tools, Systems & Communication Demonstrate expert proficiency in Excel and clinical trial management systems. Communicate effectively in both written and verbal formats, incorporating feedback seamlessly. Maintain accurate and timely updates in departmental trackers and databases.
• Compliance, Collaboration & Continuous Improvement Deepen and maintain knowledge of GCP, sponsor processes, SOPs, work instructions, and new technologies. Build strong working relationships with internal and external partners. Support and train additional team members as needed. Contribute to process improvement initiatives that simplify workflows and eliminate inefficiencies. Take on ad‑hoc tasks and diverse projects with a solutions‑oriented mindset.

Benefits

• We reward and recognize our people by providing valuable benefits and a quality-of-life balance.
• The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time.
• Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work.
• Syneos complies with all applicable federal, state, and municipal paid sick time requirements.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 5,001-10,000 employees