Senior Staff/Principal Scientist, Organic Chemistry & Biochemistry

Fapon • Pleasanton, CA

53d

About The Position

We are seeking a talented and passionate Senior Staff/Principal Scientist to join our growing team. You will lead chemistry efforts to develop multi-step chemical processes that will be implemented in our groundbreaking technology. As part of a fast-paced and collaborative startup environment, you will work closely with a multidisciplinary team to build core chemistry solutions for our sequencing technology.

Requirements

• Ph.D. in organic chemistry, biochemistry, medicinal chemistry, or chemical engineering with at least 10 years of professional experience in a biotech or pharma environment.
• A thought leader in protein and nucleic acid chemistry.
• Extensive experience in developing novel chemical methodologies for proximity ligation, surface/beads chemistry, assay development, protein (orthogonal) conjugation, proteomics sample preparation, post-translational modifications, solid-phase synthesis, and advanced purification techniques.
• Deep understanding of Edman degradation in protein sequencing chemistry.
• Good relationship with commercial resources providing services of analytical analysis of both small molecules and macromolecules.
• Strong problem-solving skills and the ability to work both independently and within a team.
• Excellent people skills and presentation skills.
• Willing and capable of being hands-on in the wet-lab

Responsibilities

• Contribute as a full-time bench scientist and a leader of the chemistry team
• Design, implement, and adjust strategies & R&D plans in developing chemistries for a non-mass spec-based proprietary proteomics workflow
• Develop, verify, optimize protocols to accommodate cross-functional processes including automation
• Manage and prioritize multiple timelines across diverse projects/goals in coordination with other functional progress
• Communicate the overall chemistry strategy and rationale to external parties
• Proactively seek innovation - build and expand a technology pipeline & IP portfolio
• Actively identify, build, and secure internal and external resources to support R&D work
• Create and maintain a scientific advisory group to support R&D work
• Participate in multidisciplinary team activities, commit to rapid identification and resolution of problems, and advance projects through critical internal review processes
• Review research papers and intellectual property literature in support of ongoing research projects

Benefits

• Financial security through competitive compensation, incentives, and a retirement plan
• Health care and well-being programs, including competitive medical, dental, vision, life and long-term disability insurance.
• Generous paid time off including vacation, sick time, and holidays
• 401(k) retirement savings with a company match
• We continue to optimize our benefits & wellness programs as we grow our organization to make sure they meet our diverse workforce needs.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree
• Number of Employees: 1,001-5,000 employees