Senior Site Contracts Manager (Sponsor Dedicated /Remote – US Based)

Syneos Health•Roxboro, NC

4d•Remote

About The Position

Senior Site Contracts Manager (Sponsor‑Dedicated /Remote – US Based) Are you a contracts expert who thrives on navigating complexity, building strong site partnerships, and driving timelines forward? Syneos Health is seeking a Senior Site Contracts Manager to support a sponsor‑dedicated program focused on high‑impact Pharma & Vaccine studies. If you’re energized by problem‑solving, negotiation, and leading projects across multiple therapeutic areas—especially oncology—we’d love to meet you. About the Role: As a Senior Site Contracts Manager, you’ll serve as a strategic expert responsible for developing, negotiating, and managing US site budgets and clinical trial agreements. You’ll collaborate closely with internal teams, external stakeholders, and major academic institutions to craft robust contracts that support operational excellence while minimizing risk. This role is perfect for a communicator, leader, and negotiator who’s ready to hit the ground running and make an immediate impact.

Requirements

4+ years building budgets and contracts from templates
Direct experience negotiating with large academic institutions
Ability to juggle priorities, lead projects, and deliver results under tight timelines
Strong understanding of clinical study protocols, timelines, and site‑related milestones (e.g., SIV)
Bachelors degree

Nice To Haves

Oncology therapeutic area experience
Prior experience with pharma, CRO, or investigative sites
Strong project management skills and comfort leading cross‑functional efforts

Responsibilities

Budgeting & Template Development Build US site budget templates and study‑specific budget language for Pharma & Vaccine clinical trials. Develop and refine templates to support consistency, compliance, and strategic study needs.
Contract Negotiation & Risk Management Lead direct negotiations with large academic institutions and other critical stakeholders. Draft and finalize clinical trial agreements that balance business objectives with legal and operational protections. Conduct due diligence checks—such as FMV assessments and site justification reviews—when initial offers are declined. Determine when requests require budget or language escalation and secure appropriate approvals.
Project Leadership & Delivery Prioritize and lead multiple contracting projects across several therapeutic areas (oncology experience strongly preferred). Proactively escalate risks, timeline impacts, or delays that could affect CTA execution.
Tools, Systems & Communication Demonstrate expert proficiency in Excel and clinical trial management systems. Communicate effectively in both written and verbal formats, incorporating feedback seamlessly. Maintain accurate and timely updates in departmental trackers and databases.
Compliance, Collaboration & Continuous Improvement Deepen and maintain knowledge of GCP, sponsor processes, SOPs, work instructions, and new technologies. Build strong working relationships with internal and external partners. Support and train additional team members as needed. Contribute to process improvement initiatives that simplify workflows and eliminate inefficiencies. Take on ad‑hoc tasks and diverse projects with a solutions‑oriented mindset.

Benefits

We are passionate about developing our people, through career development and progression; supportive and engaged line management; technical and therapeutic area training; peer recognition and total rewards program.
We are committed to our Total Self culture – where you can authentically be yourself. Our Total Self culture is what unites us globally, and we are dedicated to taking care of our people.
We are continuously building the company we all want to work for and our customers want to work with.
The benefits for this position may include a company car or car allowance, Health benefits to include Medical, Dental and Vision, Company match 401k, eligibility to participate in Employee Stock Purchase Plan, Eligibility to earn commissions/bonus based on company and individual performance, and flexible paid time off (PTO) and sick time.
Because certain states and municipalities have regulated paid sick time requirements, eligibility for paid sick time may vary depending on where you work.
Syneos complies with all applicable federal, state, and municipal paid sick time requirements.

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