Senior Scientist

Bioqual•Rockville, MD

48d

About The Position

The Senior Scientist will work with a team to oversee all aspects of the protocol, experimental data, unforeseen problems, test systems and any specific regulations that must be followed. This will include interacting with clients, performing business development, acting as the study director and may prepare and oversees budgets. In addition the Sr. Scientist will play a critical role in advancing our research programs through scientific expertise, technical proficiency and collaborative problem-solving.

Requirements

Ph.D. Cell Biology, Molecular Biology, Pharmacology, Immunology or related field with a 8+ years of relevant experience, or M.S with 15+ years of experience.
Proven expertise in 3D organoid culture techniques, including patient-derived organoids and microphysiological systems
Strong background in developing and executing high-throughput in vitro assays.
Proficiency in data analysis software and electronic lab notebooks.
Excellent problem-solving skills and the ability to work independently and collaboratively in a fast-paced environment.
Strong written and verbal communication skills for presenting data and authoring technical reports.
Demonstrated ability to work collaboratively with interdisciplinary teams.
Commitment to staying current with emerging technologies and methodologies in assay development and screening.
Proven experience in designing, optimizing, and executing high-throughput screening assays for lead molecule discovery and early-stage drug development.
Experience with automated liquid handling systems and high-content imaging platforms.
Familiarity with regulatory requirements for preclinical assay validation.
Statistical Design of Experiments (DoE): Knowledge of experimental design principles to optimize assay conditions and ensure robustness.
Regulatory Compliance: Understanding of GLP practices and experience in preparing documentation for regulatory.
Experience in a CRO or industry-based research setting.

Responsibilities

Design, develop, and validate complex vitro assays, including 3D organoid models, to evaluate drug efficacy and toxicity.
Collaborate cross-functionally with internal teams to integrate in vitro findings into broader preclinical studies and ensure timely delivery of projects, maintain quality standards and meeting tight deadlines.
Engage directly with sponsors to understand their specific needs, providing tailored assay solutions and ensuring high levels of client satisfaction.
Manage multiple projects simultaneously and adapt to evolving priorities in a fast- paced environment.
Implement high-throughput screening (HTS) methodologies to facilitate large-scale compound testing, as applicable.
Lead the expansion and optimization of in vitro assay offerings in alignment with evolving market demands and sponsor requirements.
Stay abreast of industry trends and technological advancements to inform strategic decisions and maintain a competitive edge in assay development services.
Maintain accurate and detailed experimental records and contribute to technical reports and publications.

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