Senior Scientist, Translational Science & Biomarkers
About The Position
ImmunEdge has an exciting opportunity for an experienced biomarker scientist with histopathology expertise to join our Translational Science & Biomarkers team. This person will contribute to preclinical and future clinical programs by developing and validating tissue-based biomarker assays. Strong candidates will be highly collaborative, strategically organized, and passionate about drug discovery and precision medicine. Expertise in immunology, oncology, and spatial biology are important for this role, and candidates should have experience working with human clinical samples.
Requirements
- Ph.D. in Immunology, Pathology, Molecular and Cellular Biology, or a related field, or M.S. with additional years of experience
- 4+ years of industry experience in oncology drug development, with at least 5 years of total experience working in histology and IHC labs with FFPE samples
- Strong technical expertise in histopathology, including multiplex technologies, spatial transcriptomics, and digital pathology image analysis
- Proficiency with other standard lab techniques including tissue culture, ELISA, qPCR, western blot, and flow cytometry
- Ability to independently oversee scientific activities, solve complex problems, and rigorously analyze and interpret scientific data
- Ability to work effectively and collaboratively in a supportive, but dynamic, start-up environment
- Excellent communication, technical writing, record-keeping, and organizational skills
Nice To Haves
- Experience with bioanalytical (PK) assay development, primary immune cell culture, and experience with the Leica Bond Rx platform would be a plus
Responsibilities
- Build our understanding of gene and protein expression profiles for novel oncology biomarkers (ImmunEdge targets and relevant cell types) across different body tissues and tumor types, to help guide future clinical development
- Design, validate, and implement single and multiplex immunohistochemistry and ISH assays, including co-proximity assays (e.g. DuoLink PEA)
- Manage histopathology lab operations, including organization of reagents and specimens, equipment maintenance, coordinating with vendors, etc.
- Identify and assess emerging pathology techniques, including spatial transcriptomics and novel multiplex technologies, and either build these capabilities in-house or oversee work performed at CROs
- Develop and run digital image analysis workflows for whole slide scans, using software such as HALO or Visiopharm
- Contribute to scientific strategy by proposing new hypotheses and supporting the advancement of ImmunEdge’s research and development pipeline
- Analyze, interpret, and communicate complex research findings to cross-functional stakeholders with varied scientific backgrounds
- Maintain accurate, well-organized records while supporting a safe and compliant lab environment
Benefits
- ImmunEdge offers a competitive employment package that includes an annual bonus plan, equity, and a generous benefits package including comprehensive health (medical, dental, and vision) insurance for our employees and their families, a 401k plan, FSA plans (medical, dependent), an Employee Assistance Plan, and a holiday and paid time off plan.
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Education Level
Ph.D. or professional degree
