Senior Scientist, TCR Therapy
About The Position
Join our pioneering team in Gaithersburg, MD, as a Senior Scientist dedicated to advancing personalized TCR therapies targeting patient-specific cancer antigens for solid tumors. In this impactful role, you will lead cutting-edge scientific initiatives to refine our TCR platform and translate it into scalable clinical therapies, directly contributing to BioNTech's mission of transforming patient outcomes through innovative immunotherapy solutions. You will thrive in a collaborative and dynamic environment that values scientific rigor and innovation. As part of a global network of experts, your contributions will shape the future of personalized therapies and make a meaningful difference in patients' lives.
Requirements
- PhD in Immunology, Biomedical Sciences, or related field with deep expertise in tumor immunology or TCR/neoantigen biology
- Proficiency in immunological techniques such as T cell functional assays, FACS analysis, IncuCyte assays, and cell line engineering
- Advanced computational skills (Python/R) with knowledge of AI/ML applications in immunology or experience collaborating with AI/ML teams
- Strong organizational skills with meticulous experimental documentation
- Proven ability to excel in fast-paced environments while adapting to evolving priorities
Nice To Haves
- experience with personalized immunotherapies or spatial biology approaches like spatial transcriptomics
- US based candidates expected
Responsibilities
- Design and execute studies to enhance our TCR platform, focusing on multiplexed TCR delivery meeting safety, efficacy, and scalability standards
- Establish, optimize, and troubleshoot high-throughput workflows supporting discovery, screening, and validation activities
- Drive innovation by adopting novel technologies and methodologies aligned with evolving scientific and clinical needs
- Lead cross-site and cross-functional collaborations to ensure timely delivery of project milestones
- Mentor team members while fostering a high-performance culture and professional development
- Communicate findings effectively through tailored presentations for executive and technical audiences
Benefits
- Medical, Dental and Vision Insurance
- Life, AD&D, Critical Illness Insurance
- Pre-tax HSA & FSA, DCRA Spending Accounts
- Employee Assistance & Concierge Program (EAP) available 24/7
- Parental and Childbirth Leave & Family Planning Assistance
- Sitterstream: Virtual Tutoring & Childcare Membership
- Paid Time Off: Vacation, Sick, Bereavement, Holidays (including Floating) & Year-End U.S. Shutdown.
- 401(K) Plan with Company Match
- Tuition Reimbursement & Student Loan Assistance Programs
- Wellbeing Incentive Platforms & Incentives
- Professional Development Programs
- Commuting Allowance and subsidized parking
- Discounted Home, Auto & Pet Insurance
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What This Job Offers
Job Type
Full-time
Career Level
Senior
Education Level
Ph.D. or professional degree
