Senior Scientist-Synthetic Chemist

Amgen • Thousand Oaks, CA

114d • Hybrid

About The Position

Join Amgen's Mission of Serving Patients. At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas - Oncology, Inflammation, General Medicine, and Rare Disease - we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives. Our award-winning culture is collaborative, innovative, and science-based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Requirements

• Doctorate degree (PhD, PharmD, or MD) or Master's degree with 3 years of relevant experience, or Bachelor's degree with 5 years of relevant experience.

Nice To Haves

• Ph.D. in synthetic organic chemistry or related discipline with postdoctoral or >2 years industry experience.
• Expertise in small molecule or carbohydrate synthesis.
• Demonstrated hands-on laboratory experience preparing a diverse range of synthetic compounds.
• Ability to collaborate with oligonucleotide chemists, conjugation chemists, and biologists.
• Experience with state-of-the-art techniques and characterization of synthetic molecules.
• Strong communication and teamwork skills in a dynamic environment.

Responsibilities

• Develop the next generation of RNA therapeutics as part of the oligonucleotide delivery team.
• Utilize state-of-the-art methods to design and prepare novel delivery ligands, conjugation linkers, and nucleotides.
• Chemically modify oligonucleotides for enhanced delivery and efficacy.
• Interact with oligonucleotide chemists, conjugation chemists, protein chemists, and biologists to discover novel delivery mechanisms.
• Contribute to the therapeutic RNA pipeline.

Benefits

• Comprehensive employee benefits package including health and welfare plans.
• Retirement and Savings Plan with generous company contributions.
• Group medical, dental, and vision coverage.
• Life and disability insurance.
• Flexible spending accounts.
• Discretionary annual bonus program.
• Stock-based long-term incentives.
• Award-winning time-off plans.
• Flexible work models, including remote and hybrid work arrangements.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Industry: Chemical Manufacturing
• Education Level: Ph.D. or professional degree