Pfizer-posted about 1 year ago
$88,300 - $147,100/Yr
Full-time • Entry Level
Groton, CT
Chemical Manufacturing

The position is for a creative and motivated chemist with expertise in biocatalysis to join the Chemical Research and Development (CRD) laboratories at Pfizer in Groton, CT. The successful candidate will contribute to the development of innovative enzymatic processes for synthesizing active pharmaceutical ingredients (APIs). This role involves working collaboratively with multidisciplinary teams to design novel enzyme platforms and optimize biocatalytic reactions, ensuring compliance with process chemistry targets and advancements in biocatalysis technology.

  • Independently develop new enzymatic platforms, protocols, and procedures compatible with process chemistry targets.
  • Expertly use enzyme classes relevant to biocatalysis applications in Pharma, including enzyme screening and protein engineering.
  • Perform scientific experiments with clear objectives and maintain high compliance in documenting research using electronic notebooks.
  • Participate in brainstorming sessions to propose innovative enzymatic and organic reactions for API synthesis.
  • Maintain contemporary knowledge of relevant primary literature in biocatalysis and synthetic chemistry.
  • Coach, mentor, train, supervise, and develop staff when assigned; participate in recruiting when needed.
  • Collaborate with chemists, analysts, and chemical engineers to design novel enzyme processes.
  • Prepare research reports, technical presentations, and external publications.
  • PhD in chemistry with 0-5 years' experience in the pharma industry.
  • Experience applying biocatalysis in a laboratory setting and familiarity with developing pharmaceutical processes using biocatalysis.
  • Subject matter expert in a broad range of enzymes in organic chemistry and enzyme engineering.
  • Experience designing and optimizing biocatalytic reactions and high-throughput screening in multi-well plates.
  • 401(k) plan with Pfizer Matching Contributions
  • Paid vacation, holiday, and personal days
  • Paid caregiver/parental and medical leave
  • Health benefits including medical, prescription drug, dental, and vision coverage
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