Senior Scientist, Molecular Biology

AstraZeneca • Gaithersburg, MD

2d • Onsite

About The Position

Are you passionate about advancing our understanding of genetic analysis and biomarker detection? Join AstraZeneca, in Gaithersburg, Maryland, as a Senior Scientist, within the Clinical Pharmacology and Safety Sciences (CPSS) Cell Therapy team, specializing in molecular biology technologies, where your technical expertise will enhance our extensive portfolio in Cell and Gene Therapy.

Requirements

• Education: PhD in molecular biology, genetics, or related fields preferred, with 0-2+ years of relevant experience. Alternatively, an M.Sc. with 3-5+ years, or a B.Sc. with 6-7+ years of experience in relevant areas.
• Technical Expertise: Demonstrated expertise in molecular biology techniques, including isolation of DNA/RNA in various cell/tissue types, ability to independently design primers tailored for use across diverse technologies, developing, qualifying, and validating assays for bioanalytical characterization in pre-clinical and clinical studies within a GxP laboratory.
• Data Analysis Skills: Proficient in analyzing complex datasets using analysis software.
• Collaboration Experience: Experience working with internal teams and external partners to facilitate technology transfers and oversee assay validations.
• Project Management: Ability to manage multiple concurrent projects in a fast-paced environment, demonstrating strong accountability, organizational skills, and effective leadership. Maintain accurate records and documentation of all results.
• Communication Skills: Outstanding verbal and written communication skills to articulate complex data and strategies to various audiences. Present findings to project teams and stakeholders in a clear and concise manner.

Responsibilities

• Assay Execution and Data Analysis: Implement complex molecular bioanalytical methods using PCR and ddPCR/dPCR technologies.
• Manage technology transfers to established CRO partners and ensure assays are precise and reliable by conducting detailed data reviews and troubleshooting as needed.
• Responsible for authoring and reviewing method development reports, SOPs, and analytical method protocols.
• Cross-Department Collaboration: Innovate and develop advanced bioanalytical techniques through robust collaboration within and across departments. Your contributions will be integral across the entire AZ portfolio within Cell and Gene Therapy.
• Project and Stakeholder Management: Operate effectively in a dynamic, matrixed environment to manage stakeholder expectations and influence project strategy and delivery. Collaborate with skilled bioanalytical scientists and partnered laboratories.
• Strategic Development: Support assay development in conjunction with bioanalytical strategy leads, ensuring assays meet strategic objectives.
• Scientific Leadership: Enhance AstraZeneca's scientific reputation within CPSS Cell Therapy through data interpretation, presenting at professional conferences, and publishing research findings. Stay current with industry trends and advancements in assay technologies and incorporate relevant updated into assay development strategies.

Benefits

• Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees