Senior Scientist, Mammalian Cell Line Engineering and Expression Optimization for ADCs, Bispecifics, with Focus on Non Natural Amino Acid Expression Systems

AstraZeneca•Gaithersburg, MD

About The Position

Typical Accountabilities: • Applies technical knowledge and expertise to achieve project targets in a timely fashion and to agreed quality standards • Develops and maintains a level of scientific knowledge and capability, perhaps extending to specialist expertise in a specific area of work • Represents specialism on relevant projects teams, ensuring the provision of appropriate and timely data to the team • Independently, designs and carries out analytical studies and experiments that require expert knowledge, and develops and validates appropriate test methodology and specifications to achieve project aims • Independently, assesses and reports data with a clear understanding of its reliability, interprets findings and draws authoritative conclusions and recommendations so that their significance can be appreciated • Provides training /guidance to junior scientists on technical and functional processes • Helps to develop new and innovative techniques and methodologies and draws up relevant investigations • Liaises with colleagues from other disciplines with the purpose of discussing project-related matters, sharing experiences and reporting progress • Contributes to the management of external collaborations, e.g. consultants and contract research organisations • Uses own knowledge and expertise to input into management decisions about channelling resources to reduce risk associated with inappropriate investment decisions • Develops own level of scientific competence by keeping abreast of relevant scientific developments, by collaborating with peer scientists or through contacts with external groups • Ensures that work is performed in accordance with appropriate Safety, Health & Environment (SHE), quality and compliance standards, e.g. Good Laboratory Practice (GLP) Typical People Management Responsibility (direct / indirect reports): • Approximate number of people managed in total (all levels) - 0 What is the global remit? (how many countries will the role operate in?): • Own country AstraZeneca is a global, science-led, patient-focused biopharmaceutical company. We focus on discovering, developing and commercialising prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science, challenge convention and unleash your entrepreneurial spirit. To embrace differences and take bold actions to drive the change needed to meet global healthcare and sustainability challenges. There is no better place to make a difference in medicine, patients, and society. An inclusive culture where you will connect different thinking to generate new and valuable opportunities. Where you will find a commitment to lifelong learning, growth and development for all. Our Inclusion & Diversity (I&D) mission is to create an inclusive and equitable environment where people belong, using the power of our diversity to push the boundaries of science to deliver life-changing medicines to patients. Inclusion and diversity are fundamental to the success of our company, because innovation requires breakthrough ideas that only come from a diverse workforce empowered to challenge conventional thinking. We’re curious about science and the advancement of knowledge. We find creative ways to approach new challenges. We’re driven to make the right choices and be accountable for our actions. As an organisation centred around what makes us human, we put a big focus on people. Across our business, we want colleagues to wake up excited about their day at the office, in the field, or in the lab. Along with our purpose to bring life-changing medicines to people across the globe, we have a promise to you: to help you realise the full breadth of your potential. Here, you’ll do work that has the potential to change your life and improve countless others. And, together with your team, you’ll shape a culture that unites and inspires us every day. This is your life at AstraZeneca.

Requirements

Bachelors degree or equivalent and relevant experience within the discipline
Experience in the pharmaceutical industry
Understanding of current principles and concepts in own area of work
Understanding of regulations and relevant compliance systems related to own area of work
General understanding of other Discovery / R&D disciplines and their role in achieving the objectives of research area
Understanding of patent and IP issues

Nice To Haves

Specialist knowledge in a specific area related to Chemistry

Responsibilities

Applies technical knowledge and expertise to achieve project targets in a timely fashion and to agreed quality standards
Develops and maintains a level of scientific knowledge and capability, perhaps extending to specialist expertise in a specific area of work
Represents specialism on relevant projects teams, ensuring the provision of appropriate and timely data to the team
Independently, designs and carries out analytical studies and experiments that require expert knowledge, and develops and validates appropriate test methodology and specifications to achieve project aims
Independently, assesses and reports data with a clear understanding of its reliability, interprets findings and draws authoritative conclusions and recommendations so that their significance can be appreciated
Provides training /guidance to junior scientists on technical and functional processes
Helps to develop new and innovative techniques and methodologies and draws up relevant investigations
Liaises with colleagues from other disciplines with the purpose of discussing project-related matters, sharing experiences and reporting progress
Contributes to the management of external collaborations, e.g. consultants and contract research organisations
Uses own knowledge and expertise to input into management decisions about channelling resources to reduce risk associated with inappropriate investment decisions
Develops own level of scientific competence by keeping abreast of relevant scientific developments, by collaborating with peer scientists or through contacts with external groups
Ensures that work is performed in accordance with appropriate Safety, Health & Environment (SHE), quality and compliance standards, e.g. Good Laboratory Practice (GLP)

Benefits

qualified retirement program [401(k) plan]
paid vacation and holidays
paid leaves
health benefits including medical, prescription drug, dental, and vision coverage

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