Senior Scientist II

AbbVie • Worcester, MA

403d

About The Position

The purification scientist role at AbbVie involves leading the development and optimization of purification processes for biologics candidates. This position is critical for supporting both early and late-stage therapeutic protein development, utilizing advanced technologies and collaborative strategies to enhance lab efficiency and project outcomes. The ideal candidate will thrive in a dynamic, onsite lab environment, engaging in cross-functional teamwork to drive innovative solutions in purification processes.

Requirements

• Degree in Chemical Engineering, Biochemistry, Chemistry or other sciences with Bachelor's Degree or equivalent education and typically 12 years of experience, MS or equivalent education and typically 10 years of experience, PhD and typically 4 years of experience
• Experience in purification process development
• Expertise in developing standard bioprocess unit operations such as chromatography separations and filtration operations
• Proficient in writing methods and operating AKTA chromatographic instruments
• Able to independently design, execute, and interpret laboratory experiments
• Strong understanding of analytical techniques, such as HPLC
• Excellent attention to detail and ability to keep detailed written records
• Proven record of authoring publications, technical reports, regulatory documents, and presentations
• Strong communication skills including verbal, written, and scientific data presentation
• Proficiency with Microsoft Office software

Nice To Haves

• Direct experience leading tech transfer of downstream processes to GMP and/or pilot scale for mAb or other mAb-based biologics
• Direct experience in executing process characterization studies, including use of statistical software to design, analyze, and interpret characterization results

Responsibilities

• Effectively function as a senior scientist, generating original technical ideas and research or development strategies
• Lead development, optimization, scale-up, and tech transfer of purification processes for biologics candidates to support early and late-stage development
• Represent purification development team and actively influence development strategy on cross-functional CMC teams
• Work efficiently, collaboratively, and cross-functionally toward project timelines and goals
• Demonstrate creative 'out of the box' thinking to solve difficult problems and champion new technologies to achieve project goals
• Be hands-on and execute lab operations in collaboration with direct reports and/or purification development team members to meet project deliverables
• Transfer processes to pilot and GMP manufacturing
• Work with contract labs and carry out viral clearance studies
• Generate new scientific proposals and lead those efforts
• Write technical publications, reports, presentations, and regulatory filings
• Mentor/supervise a team and evaluate the performance of those individuals

What This Job Offers

• Job Type: Full-time
• Industry: Chemical Manufacturing
• Education Level: Bachelor's degree