Senior Scientist II, Biologics Purification

AbbVie • North Chicago, IL

10d

About The Position

Join AbbVie’s Biologics Discovery Sciences group and make a tangible impact in advancing innovative biologic therapies. As a scientist specializing in Biologics Purification, you will play a pivotal role in driving drug discovery, collaborating within a dynamic team dedicated to supporting transformative science that improves patient lives worldwide. Your expertise will help deliver high-purity bispecific candidates with suitable purity/characteristics to support the advancement of vital in vitro (i.e. drug-like property assays, binding, cell-based assays, etc.) and in vivo studies (i.e. efficacy, non-GLP NHP PK, DRF, etc.).

Requirements

• BS, MS, or PhD in Bioinformatics, Biophysics, Chemical Engineering, or related field with typically 12+ years (BS), 10+ years (MS), or 4+ years (PhD) of experience
• Deep proficiency in large-scale bioprocessing and chromatography
• Skilled in software systems and/or programming languages: Unicorn, Chromeleon, Empower, JMP, Minitab, Python, SDMS platforms
• Experience with in silico tools/models and DOE to both predict and optimize protein separation behavior based upon critical process parameters.
• Strong understanding of molecular and post-translational attributes of biologics
• Exceptional analytical, communication, and presentation skills
• Collaborative spirit and dedication to scientific excellence

Nice To Haves

• Experience with data extraction API, ETL tools and LIMS platforms for data acquisition, integration, and management across multiple analytical platforms is a plus

Responsibilities

• Lead the purification of bispecific biologics to support critical research assays and studies
• Design and execution of robust process development strategies necessary to address production liabilities which factor into future process scalability.
• Apply advanced bioprocessing and chromatography techniques at large scale
• Utilize in silico tools, DOE methodologies, and predictive modeling to optimize protein separation and maximize yield/quality
• Integrate and manage analytical data using LIMS, ETL tools, and data extraction APIs
• Collaborate with multidisciplinary teams, translating molecular insights into functional results
• Stay current with emerging scientific literature to foster innovation and continuous improvement
• Present findings clearly to diverse audiences and document results with rigor

Benefits

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our short-term incentive programs.
• This job is eligible to participate in our long-term incentive programs.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level