Senior Scientist I, Peptide Purification

AbbVie • Madison, WI

119d

About The Position

We are seeking a highly motivated Peptide Purification Scientist to join our Peptide Synthesis team. The ideal candidate will have hands-on experience in the synthesis, transformation, and purification of peptides. This individual will investigate, identify, develop, and optimize new methods/techniques to generate reliable and reproducible data in a timely manner. The candidate should also be able to demonstrate broad and versatile technical expertise within discipline and be able to collaborate and communicate with other groups across discipline.

Requirements

• Bachelor's Degree or equivalent education and typically, 10 years of experience, Master's Degree or equivalent education and typically 8 years of experience, PhD and no experience necessary.
• Possess thorough theoretical and practical understanding in peptide purification and HPLC method development; experience in peptide synthesis is highly desirable.

Responsibilities

• Perform routine laboratory techniques: pipetting, reagent reconstitution, calculation of concentrations/dilutions, and accurate weighing of raw materials for instrument setup and compound processing.
• Use RP-HPLC/MS for purification, characterization, and analysis of peptides.
• Setup, maintain, and troubleshoot instruments: HPLC, lyophilizers, peptide synthesizers, centrifuges, rotovap, and balances.
• Maintain and optimize peptide purification processes to ensure consistent output, with a strong focus on increasing peptide recovery and overall throughput.
• Follow SOPs for standardized activities; implements data driven improvements/optimization.
• Identify and implement process improvements; conduct optimization experiments when necessary.
• Troubleshoot and correct process or instrument issues.
• Complete hazardous waste training (RCRA/DOT) and manage hazardous waste, including bulking and coordination with handlers.
• Maintain accurate lab notebooks and records of all procedures.
• Analyze and interpret LC/MS data to assess peptide/sample quality.
• Adjust analytical methods for QC and peptide content.
• Contribute to development of new data analysis methods.
• Prepare and review technical reports, SOPs, summaries, and quantitative analyses.
• Manage inventory of reagents and consumables; order supplies as needed.
• Train new employees in lab techniques and instrument use.
• Comply with all corporate/divisional policies and procedures.

Benefits

• Paid time off (vacation, holidays, sick)
• Medical/dental/vision insurance
• 401(k) to eligible employees
• Short-term incentive programs
• Long-term incentive programs

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Industry: Chemical Manufacturing
• Education Level: Bachelor's degree