Senior Scientist I - Chemistry

AbbVie • North Chicago, IL

284d

About The Position

The AbbVie Process Chemistry Chromatographic Separations Lab is actively seeking a Sr. Scientist I with experience in analytical and preparative chromatographic method development. Our team collaborates with colleagues across multiple disciplines, offering expertise in preparative chromatography to support a broad range of AbbVie R&D programs. We maintain and utilize specialized equipment for a variety of separation tasks, including the purification of peptides, ADC drug-linkers, and chiral compounds, as well as the isolation of low-level small molecule API impurities. Additionally, the team is responsible for pilot-scale preparative purification, developing scalable purification processes, and overseeing their implementation under cGMP guidelines at AbbVie's North Chicago Chemical Pilot Plant. This role will contribute to the development of novel/advanced separations technologies and broader efforts to develop new process technologies for advancing the AbbVie pipeline, including the application of machine learning strategies. We are looking for a highly motivated scientist capable of conceiving, implementing, and executing novel research and development projects. Ideal candidates will have hands-on experience developing chromatographic methods and troubleshooting complex separation challenges. Experience working with peptides is highly desirable, though not strictly required for application.

Requirements

• Bachelor's, Master's, or PhD Degree in chemistry or chemical engineering with typically 10+ (BS), 8+ (MS) or 0+ (PhD) years of experience.
• Strong technical background in Separations Science. Capable of independently developing and troubleshooting chromatographic methods.
• A broad range of functional expertise in modern analytical analysis techniques with an emphasis on chromatography, compound purification, spectral analysis and interpretation.
• An ability to search chemical literature and evaluate potential solutions to research problems.
• High-quality written and oral communication skills and ability to interact effectively with interdisciplinary scientists and engineers.

Nice To Haves

• Experience working with peptides.

Responsibilities

• Develop and execute purification processes to support the clinical development of potential therapies, including small molecules, antibody drug conjugates, and peptides.
• Routinely demonstrate scientific initiative and creativity in research and development activities to resolve key project hurdles.
• Build strong relationships with peers and cross-functional partners to enhance performance.
• Operate with autonomy and maintain a high level of productivity in laboratory research and method development, with minimal supervision.
• Foster a learning environment, welcome diverse ideas, and encourage experimentation for improvement.
• Adhere to corporate standards for conduct, safety, quality, and proper handling of materials.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Industry: Chemical Manufacturing
• Education Level: Ph.D. or professional degree