Senior Scientist, High-Throughput Screening - San Diego, CA

dsm-firmenich • San Diego, CA

6d

About The Position

Senior Scientist High-Throughput Screening Location: San Diego, CA Join our dynamic and cutting-edge research program focused on the chemical senses. As part of our multi-disciplinary discovery team, you will collaborate with our global R&D community to explore chemosensory receptor-driven perception and its applications in taste and health. We are seeking an exceptional and goal-oriented expert in small molecule discovery in a high-throughput screening setting. The successful candidate will oversee High-throughput Screening (HTS) assay development and screening operations, including scheduling, monitoring assay performance, and data flow. The ideal candidate will have abundant experience in running GPCR and ion channel cell-based assays with excellent troubleshooting skills.

Requirements

• Ph.D. in Molecular or Cell Biology, Neuroscience, or a related field, and a minimum of 5 years of industry experience
• Proven track record of accomplishment leading scientific teams and managing scientists in an HTS or related lab environment
• Demonstrated expertise in GPCR or ion channel pharmacology and structure-function analysis, combined with advanced data analysis capabilities
• Ability to work collaboratively, communicate effectively, and build professional relationships in a multidisciplinary setting
• Strong organizational skills with initiative to develop new assays and streamline workflows

Responsibilities

• Ensure assay robustness and reproducibility of results.
• Supervise assay transfer from Biology to HTS group
• Supervise daily operations within the high-throughput screening and compound reformatting laboratories, ensuring efficient management of all assay processes and compound-related activities
• Review and analyze screening data to promote hits to leads in the different discovery programs and troubleshoot assay or equipment issues as they arise
• Remain current with relevant knowledge and screening technologies and contribute to the design and implementation of experiments for new HTS assays
• Foster a problem-solving mindset and devise innovative approaches to research challenges
• Work with Data Science group to enable or facilitate AI-driven operations and data analysis
• Prepare and submit scientific manuscripts, patent applications, and internal reports to top peer-reviewed journals

Benefits

• Opportunity to join a dynamic and thriving team applying Machine Learning and other modeling techniques to biology and chemistry.
• Being part of a result-oriented organization culture that fosters team collaboration and scientific excellence.
• The opportunity to contribute to projects with potentially great health and social benefits.
• The ability to be a part of a highly creative and imaginative team in an incredibly inspiring industry.
• A space to grow by encouraging and supporting curiosity and an open mindset.
• A culture that prioritizes safety and well-being, both physically and mentally.
• We offer competitive pay, career growth opportunities, and outstanding benefit programs.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees