Senior Scientist - Cell & Molecular Biology

Sanofi•Cambridge, MA

About The Position

Sanofi Intrépide Research Laboratories is an innovative initiative identifying and advancing breakthrough science, technology, and business opportunities critical to our pipeline strategy. Operating globally with sites in the US and China, we foster an entrepreneurial culture where scientific excellence drives decision-making. Our agile teams work collaboratively to accelerate the delivery of high-impact therapeutics through efficient execution and creative problem-solving. With an operating model based on start-up biotech companies, Intrepide US is validating emerging biology, technology and molecules, incubating novel mechanisms of action and approaches, and removing key scientific and technological barriers to unlock value creation. Join our dynamic US Core Team to develop and implement cellular models that recapitulate human disease biology. This role combines hands-on cell biology expertise with strategic project leadership to accelerate therapeutic discovery through physiologically relevant disease models. We deliver 4.3 billion healthcare solutions to people every year, thanks to the flawless planning and meticulous eye for detail of our Manufacturing & Supply teams. With your talent and ambition, we can do even more to protect people from infectious diseases and bring hope to patients and their families.

Requirements

Bachelor's + 8 years in biopharma OR Master's + 5 years in biopharma OR Ph.D. + 3 years post-doctoral in biopharma industry experience with demonstrated expertise in cell and molecular biology techniques.
Strong track record of using disease-relevant cellular systems
Experience with multi-omics, cellular imaging, flow cytometry, and/or high-content analysis.
Project management experience including timeline and budget oversight.
Deep understanding of cellular & molecular biology applied to human disease mechanisms.
Strong analytical and data interpretation skills.
Excellence in written and verbal communication of complex biological data.
Ability to work effectively in a fast-paced, collaborative environment.
Entrepreneurial mindset with calculated risk-taking ability.

Nice To Haves

Experience with primary human immune and other cells and/or iPSC-derived cellular models.
Experience with CRISPR-based genomic engineering.
Expertise in single-cell sequencing technologies.
Experience managing CRO relationships for cellular & molecular biology work.
Equipment procurement and cell & molecular biology lab setup experience.
Demonstrated scientific creativity and innovation.

Responsibilities

Internalize, design and/or establish in vitro and ex vivo cellular models that reflect aspects of human disease pathophysiology, with a focus on immune-mediated diseases, and use to evaluate therapeutic candidate efficacy and mechanism-of-action.
Implement advanced cell culture techniques including 3D cultures, co-cultures, and patient-derived systems, with multi-omic, imaging and other read-outs.
Establish and validate cellular biomarker assays for translational research applications.
Develop and maintain cell biology laboratory capabilities, including equipment procurement and protocol standardization.
Collaborate with CROs to implement and transfer cellular model protocols.
Interface cross-functionally with research teams to integrate cellular biology data into therapeutic development decisions.

Benefits

Bring the miracles of science to life alongside a supportive, future-focused team.
Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally.
Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

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